Rabbit anti-Human, Mouse Nurim Polyclonal Antibody | anti-NRM antibody

Nurim (Nuclear Envelope Membrane Protein, NRM)

Cat. Num. AAA610088

• Gene Names: NRM; NRM29
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: Nurim; Polyclonal Antibody; Nurim (Nuclear Envelope Membrane Protein; NRM); Anti -Nurim (Nuclear Envelope Membrane Protein; anti-NRM antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Species Crossreactivity: Mouse, Human
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.

• Applicable Applications for anti-NRM antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Positive Control: HeLa, NIH 3T3, PC3
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for anti-NRM antibody

Nurim is an inner nuclear membrane (INM) protein that is tightly associated with the inner nuclear membrane. It was first isolated in a visual screen for nuclear envelope-localizing proteins. In subcellular fractionation, nurim remained extremely tightly bound to nuclear fractions. Unlike the known nuclear envelope (NE) membrane proteins, it is neither associated with nuclear pores, nor targeted like lamin-associated membrane proteins suggesting its localization to NE by a distinct mechanism.

Product Categories/Family for anti-NRM antibody

Antibodies; Abs to Nuclear Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 25282391
• NCBI GeneID: 11270
• NCBI Accession #: NP_009174.1
• NCBI GenBank Nucleotide #: NM_007243.1
• UniProt Accession #: Q8IXM6; Q5JP57; Q5JP58; Q5JP59; Q5JP60; Q8WU45; Q9BSX3; Q9UN92; B0S7R1
• Molecular Weight: 29,379 Da
• NCBI Official Full Name: nurim
• NCBI Official Synonym Full Names: nurim (nuclear envelope membrane protein)
• NCBI Official Symbol: NRM
• NCBI Official Synonym Symbols: NRM29
• NCBI Protein Information: nurim; OTTHUMP00000029332; OTTHUMP00000164112; OTTHUMP00000164113; nuclear rim protein; nuclear envelope membrane protein
• UniProt Protein Name: Nurim
• Protein Family: Nurim
• UniProt Gene Name: NRM
• UniProt Synonym Gene Names: NRM29
• UniProt Entry Name: NRM_HUMAN

NCBI Description

The protein encoded by this gene contains transmembrane domains and resides within the inner nuclear membrane, where it is tightly associated with the nucleus. This protein shares homology with isoprenylcysteine carboxymethyltransferase enzymes. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

Uniprot Description

NRM: contains transmembrane domains and resides within the inner nuclear membrane, where it is tightly associated with the nucleus. This protein shares homology with isoprenylcysteine carboxymethyltransferase enzymes. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6p21.33

Cellular Component: nucleoplasm; membrane; integral to membrane; nuclear inner membrane; nuclear envelope; nucleus