Western Blot (WB)
(Western blot analysis of FLIP in K562 cell lysate with FLIP at (A) 1 and (B) 2 ug/ml.)
Rabbit anti-Mouse mFLIP Polyclonal Antibody
mFLIP, CT (FLICE Inhibitory Protein)
Reactivity
Mouse
Applications
Western Blot
Purity
PurifiedPurified IgG
Synonyms
mFLIP; Polyclonal Antibody; CT (FLICE Inhibitory Protein); Anti -mFLIP; anti-mFLIP antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
A 55kD band can be detected. FLIP has short form (FLIPS) and long form (FLIPL) and recognizes the FLIPL only.
Purity/Purification
Purified
Purified IgG
Purified IgG
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Applicable Applications for anti-mFLIP antibody
Western Blot (WB)
Immunogen
Peptide corresponding to amino acids 449 to 465 of mouse FLIPL/CASHa (2,6).
Preparation and Storage
4 degree C (-20 degree C Glycerol)
Western Blot (WB)
(Western blot analysis of FLIP in K562 cell lysate with FLIP at (A) 1 and (B) 2 ug/ml.)
Western Blot (WB)
(Western blot analysis of FLIP in K562 cell lysate with FLIP at (A) 1 and (B) 2 ug/ml.)
Immunocytochemistry (ICC)
(Immunocytochemistry of FLIP in 3T3 cells with FLIP at 5g/mL.)
Immunocytochemistry (ICC)
(Immunocytochemistry of FLIP in 3T3 cells with FLIP at 5g/mL.)
Related Product Information for anti-mFLIP antibody
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD) containing adapter molecules and members of the ICE/CED-3 protease family. Caspases-8 (FLICE) and -10 (FLICE2) are two pivotal members in the ICE/CED-3 protease family. FLICE-inhibitory proteins were identified in virus and human and designated v-FLIPs and FLIP respectively (1,2). The human FLIP was also cloned by several labs independently and termed Casper, I-FLICE, FLAME-1, CASH, CLARP and MRIT (3-8). FLIP contains two death effector domains (DEDs) and a caspase-like domain. FLIP interacts with adapter protein FADD and caspase-8 and -10, and potently inhibits apoptosis induced by all known death receptors CD95, DR3, TRAIL-R and TNFR1.
Product Categories/Family for anti-mFLIP antibody
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Product Notes
The mFLIP (Catalog #AAA618771) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The mFLIP, CT (FLICE Inhibitory Protein) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's mFLIP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the mFLIP for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "mFLIP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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