Western Blot (WB)
(Western Blot (WB) analysis of MAL pAb at 1:500 dilutionLane1:Myla2059 whole cell lysate (40ug) Lane2:HuT78 whole cell lysate (40ug) Lane3:The Spleen tissue lysate of Rat (40ug) Lane4:The Spleen tissue lysate of Mouse (40ug) Lane5:AML-12 whole cell lysate (40ug) Lane6:CT26 whole cell lysate (40ug))
Rabbit MAL Polyclonal Antibody | anti-MAL antibody
MAL Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
MAL; Polyclonal Antibody; MAL Polyclonal Antibody; Myelin and lymphocyte protein; T-lymphocyte maturation-associated protein; anti-MAL antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
MAL pAb detects endogenous levels of MAL protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
153
Applicable Applications for anti-MAL antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Synthetic peptide, corresponding Human MAL.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of MAL pAb at 1:500 dilutionLane1:Myla2059 whole cell lysate (40ug) Lane2:HuT78 whole cell lysate (40ug) Lane3:The Spleen tissue lysate of Rat (40ug) Lane4:The Spleen tissue lysate of Mouse (40ug) Lane5:AML-12 whole cell lysate (40ug) Lane6:CT26 whole cell lysate (40ug))
Western Blot (WB)
(Western Blot (WB) analysis of MAL pAb at 1:500 dilutionLane1:Myla2059 whole cell lysate (40ug) Lane2:HuT78 whole cell lysate (40ug) Lane3:The Spleen tissue lysate of Rat (40ug) Lane4:The Spleen tissue lysate of Mouse (40ug) Lane5:AML-12 whole cell lysate (40ug) Lane6:CT26 whole cell lysate (40ug))
Related Product Information for anti-MAL antibody
The MAL-SRF interaction displays the predicted properties of a Rho-regulated SRF cofactor. MAL is predominantly cytoplasmic in serum-starved cells, but accumulates in the nucleus following serum stimulation. Activation of the Rho-actin signaling pathway is necessary and sufficient to promote MAL nuclear accumulation. MAL N-terminal sequences, including two RPEL motifs, are required for the response to signaling, while other regions mediate its nuclear export (or cytoplasmic retention) and nuclear import. MAL associates with unpolymerized actin through its RPEL motifs. Constitutively cytoplasmic MAL derivatives interfere with MAL redistribution and Rho-actin signaling to SRF.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 16kDa
NCBI Official Full Name
myelin and lymphocyte protein isoform a
UniProt Protein Name
Myelin and lymphocyte protein
Protein Family
UniProt Gene Name
MAL
UniProt Entry Name
MAL_HUMAN
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Product Notes
The MAL mal (Catalog #AAA3006440) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAL Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MAL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the MAL mal for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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