Immunohistochemistry (IHC)
(Immunohistochemistry analysis of human spleen tissue stained with HSP90, mAb (AC88) at 10µg/ml.)
Mouse HSP90 Monoclonal Antibody | anti-Heat shock protein 90 antibody
HSP90 monoclonal antibody (AC88)
Reactivity
Human, Mouse, Rat, Beluga, C. elegans, Chicken, Dog, E Coli, Fish, Guinea pig, Hamster, Mycobacterium leprae, Monkey, Mussel, Porcine, Rabbit, Scallop, Sheep, Water mold, Fusobacterium nucleatum
Applications
Immunohistochemistry, Western Blot
Purity
Protein G affinity purified.
Synonyms
HSP90; Monoclonal Antibody; HSP90 monoclonal antibody (AC88); anti-Heat shock protein 90 antibody
Host
Mouse
Reactivity
Human, Mouse, Rat, Beluga, C. elegans, Chicken, Dog, E Coli, Fish, Guinea pig, Hamster, Mycobacterium leprae, Monkey, Mussel, Porcine, Rabbit, Scallop, Sheep, Water mold, Fusobacterium nucleatum
Clonality
Monoclonal
Isotype
IgG1
Clone Number
AC88
Specificity
Recognizes human, rat, mouse, bacteria, beluga, dog, chicken, c. elegans, fish, guinea pig, hamster, monkey, mussel, pig, rabbit, sheep, scallop and water mold HSP90. Detects a band of ~90kDa by Western blot.
Purity/Purification
Protein G affinity purified.
Form/Format
Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
Sequence Length
722
Applicable Applications for anti-Heat shock protein 90 antibody
Immunohistochemistry (IHC) (PS), Western Blot (WB)
Application Notes
Western Blot (1:1,000, ECL)
Suggested dilutions/conditions may not be available for all applications.
Detects a band of ~90kDa by Western blot.
Suggested dilutions/conditions may not be available for all applications.
Detects a band of ~90kDa by Western blot.
Immunogen
Achlya ambisexualis (water mold) Hsp90.
Preparation and Storage
Long term storage: -20 degree C
Avoid freeze/thaw cycles.
Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of human spleen tissue stained with HSP90, mAb (AC88) at 10µg/ml.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of human spleen tissue stained with HSP90, mAb (AC88) at 10µg/ml.)
Related Product Information for anti-Heat shock protein 90 antibody
The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.
Product Categories/Family for anti-Heat shock protein 90 antibody
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
83,215 Da
NCBI Official Full Name
HSP90
UniProt Protein Name
HSP90
Protein Family
UniProt Gene Name
HSP90
UniProt Entry Name
A0A0S1LIC6_MYTCO
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Product Notes
The Heat shock protein 90 hsp90 (Catalog #AAA565051) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The HSP90 monoclonal antibody (AC88) reacts with Human, Mouse, Rat, Beluga, C. elegans, Chicken, Dog, E Coli, Fish, Guinea pig, Hamster, Mycobacterium leprae, Monkey, Mussel, Porcine, Rabbit, Scallop, Sheep, Water mold, Fusobacterium nucleatum and may cross-react with other species as described in the data sheet. AAA Biotech's HSP90 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) (PS), Western Blot (WB). Western Blot (1:1,000, ECL) Suggested dilutions/conditions may not be available for all applications. Detects a band of ~90kDa by Western blot. Researchers should empirically determine the suitability of the Heat shock protein 90 hsp90 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HSP90, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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