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Structure

IDX-17119, Inhibitor

IDX-17119

Purity
>98% (HPLC)
Synonyms
IDX-17119; IDX17119; inhibitor
Ordering
Purity/Purification
>98% (HPLC)
Target
HCV
Receptor
HCV
Chemical Name
1-(4-(7-amino-5-methylpyrazolo[1, 5-a]pyrimidin-2-yl)phenyl)-3-(((2, 4-dimethylphenyl)(methoxy)phosphoryl)amino)-1H-pyrazole-4-carboxylic acid
SMILES
CC1=CC(=C(C=C1)P(=O)(NC2=NN(C=C2C(=O)O)C3=CC=C(C=C3)C4=NN5C(=CC(=NC5=C4)C)N)OC)C
Molecular Formula
C26H26N7O4P
CAS Number
1987906-92-2
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Structure

Structure
Related Product Information for IDX-17119, inhibitor
IDX-17119 is a potent, non-nucleoside, HCV NS5B RdRp inhibitor with IC50 of 0.4nM in replicon luciferase assay; shows activity against broad genotype profile: IC50= 0.0099uM, 0.2538uM, 0.1809uM and 0.0257uM on genotypes 1b, 2a, 3a and 4a, respectively.
Product Categories/Family for IDX-17119, inhibitor
References
1. Pierra Rouvii¨re C, et al. Bioorg Med Chem Lett. 2016 Sep 15; 26 (18):4536-41.

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Product Notes

The IDX-17119 (Catalog #AAA3603106) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "IDX-17119, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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