SDS-Page
CD47, Rhesus macaque Active Protein | CD47 active protein
Human CellExp CD47, Rhesus macaque Recombinant
Purity
>95% by SDS-PAGE
Synonyms
CD47; Rhesus macaque; Human CellExp CD47; Rhesus macaque Recombinant; MER6; IAP; OA3; CD47 active protein
Host
HEK293 cells
Purity/Purification
>95% by SDS-PAGE
Form/Format
Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
Gene Source
Rhesus macaque
Endotoxin
<1.0 EU per/ug
Biological Activity
Immobilized Human SIRP alpha, Fc Tag at 5 ug/mL (100 uL/well) can bind Cynomolgus/Rhesus macaque CD47, His Tag with a linear range of 4-63 ng/mL
Measured by its binding ability in a functional ELISA.
Measured by its binding ability in a functional ELISA.
Reconstitution Instruction
Reconstitute in sterile deionized water to a concentration of 50 ug/ml.
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months
Centrifuge the vial prior to opening.
Shelf life: ~12 months
SDS-Page
SDS-Page
Testing Data
Testing Data
Related Product Information for CD47 active protein
Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. Plays a role in cell adhesion modulation of integrins
Product Categories/Family for CD47 active protein
NCBI and Uniprot Product Information
NCBI GeneID
UniProt Accession #
Molecular Weight
15.8kDa
Protein Family
Similar Products
Product Notes
The CD47 (Catalog #AAA849868) is an Active Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CD47, Rhesus macaque, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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