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SDS-Page

BCMA/TNFRSF17 Active Protein | TNR17 active protein

Human CellExp BCMA/TNFRSF17, Mouse recombinant

Gene Names
Tnfrsf17; BCM; BCMA; Tnfrsf13; Tnfrsf13a
Purity
>=90% by SDS-PAGE
Synonyms
BCMA/TNFRSF17; Human CellExp BCMA/TNFRSF17; Mouse recombinant; TNFRSF17; CD269; BCM; BCMA; TNR17 active protein
Ordering
For Research Use Only!
Host
HEK293 cells
Purity/Purification
>=90% by SDS-PAGE
Form/Format
Lyophilized from 0.22 um filtered solution in 50mM Tris, 100mM Glycine, pH7.5. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
Gene Source
Mouse
Endotoxin
<1 EU/ug
Biological Activity
Immobilized Mouse BCMA at 0.5 ug/mL (100 uL/well) can bind Mouse BAFF, Mouse IgG2a Fc Tag with a linear range of 0.1-6 ng/mL
Measured by its binding ability in a functional ELISA.
Reconstitution Instruction
Reconstitute in sterile deionized water to a concentration of 50 ug/ml.
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months

SDS-Page

SDS-Page

Testing Data

Testing Data
Related Product Information for TNR17 active protein
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
19,932 Da
NCBI Official Full Name
Tumor necrosis factor receptor superfamily member 17
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 17
NCBI Official Symbol
Tnfrsf17
NCBI Official Synonym Symbols
BCM; BCMA; Tnfrsf13; Tnfrsf13a
NCBI Protein Information
tumor necrosis factor receptor superfamily member 17; B-cell maturation protein
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 17
UniProt Gene Name
Tnfrsf17
UniProt Synonym Gene Names
Bcm; Bcma
UniProt Entry Name
TNR17_MOUSE

Uniprot Description

TNFRSF17: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.

Protein type: Membrane protein, integral; Receptor, misc.; Oncoprotein

Cellular Component: membrane; integral to membrane

Biological Process: immune system process; lymphocyte homeostasis

Research Articles on TNR17

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Product Notes

The TNR17 tnfrsf17 (Catalog #AAA849951) is an Active Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "BCMA/TNFRSF17, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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