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CD47/IAP/OA3 recombinant protein
Recombinant Rhesus Macaque CD47/IAP/OA3 (N-6His-DYKDDDDK)
Purity
>95% as determined by reducing SDS-PAGE
Synonyms
CD47/IAP/OA3; Recombinant Rhesus Macaque CD47/IAP/OA3 (N-6His-DYKDDDDK); Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6; CD47/IAP/OA3 recombinant protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE
Form/Format
Lyophilized from a 0.2um filtered solution of PBS, pH7.4.
Sequence
Gln19-Glu141
Species
Rhesus Macaque
Tag
N-6His-DYKDDDDK
Endotoxin
<1.0EU per ug as determined by the LAL method.
Protein Construction
Recombinant Rhesus macaque Leukocyte Surface Antigen CD47 is produced by our Mammalian expression system and the target gene encoding Gln19-Glu141 is expressed with a 6His, DYKDDDDK tag at the N-terminus.
Preparation and Storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 degree C. Reconstituted protein solution can be stored at 4-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
This product is provided as lyophilized powder which is shipped with ice packs.
This product is provided as lyophilized powder which is shipped with ice packs.
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SDS-Page
Related Product Information for CD47/IAP/OA3 recombinant protein
CD47, also known as Integrin?Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily. Mouse CD47 is an integral membrane protein that consists of a extracellular domain (ECD) with a single Ig?like domain, five membrane-spanning regions with short intervening loops, and C?terminal cytoplasmic tail. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It plays an important role in memory formation and synaptic plasticity in the hippocampus. As a receptor for SIRPA, it binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cellcell adhesion, it enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. It may play a role in membrane transport and/or integrin dependent signal transduction. It also prevents premature elimination of red blood cells.
NCBI and Uniprot Product Information
UniProt Accession #
Molecular Weight
Mol. Mass: 15.7kDa
AP Mol. Mass: 33-55kDa
AP Mol. Mass: 33-55kDa
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Product Notes
The CD47/IAP/OA3 (Catalog #AAA2569402) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Gln19-Glu1 41. It is sometimes possible for the material contained within the vial of "CD47/IAP/OA3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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