SDS-Page
PGP active protein
PGP, human recombinant
Gene Names
PGP; PGPase
Purity
>95% by SDS-PAGE
Synonyms
PGP; human recombinant; Phosphoglycolate phosphatase; Glycerol-3-phosphate phosphatase; G3PP; Aspartate-based ubiquitous Mg (2+)-dependent phosphatase; AUM; PGP active protein
Host
E Coli
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Sequence
MGSSHHHHHHSSGLVPRGSHMGSHMAAAEAGGDDARCVRLSAERAQALLADVDTLLFDCDGVLWRGETAVPGAPEALRALRARGKRLGFITNNSSKTRaaYAEKLRRLGFGGPAGPGASLEVFGTAYCTALYLRQRLAGAPAPKAYVLGSPALAAELEAVGVASVGVGPEPLQGEGPGDWLHAPLEPDVRAVVVGFDPHFSYMKLTKALRYLQQPGCLLVGTNMDNRLPLENGRFIAGTGCLVRAVEMaaQRQADIIGKPSRFIFDCVSQEYGINPERTVMVGDRLDTDILLGATCGLKTILTLTGVSTLGDVKNNQESDCVSKKKMVPDFYVDSIADLLPALQG
Gene Source
Human
Biological Activity
Specific activity > 3,000 units/mg
Measured by its ability to hydrolyze 1nmol of p-nitrophenyl phosphate per minute at pH7.5 at 37 degree C.
Measured by its ability to hydrolyze 1nmol of p-nitrophenyl phosphate per minute at pH7.5 at 37 degree C.
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shelf life: ~12 months
Centrifuge the vial prior to opening.
Shelf life: ~12 months
SDS-Page
SDS-Page
Related Product Information for PGP active protein
Phosphoglycolate phosphatase, also known as PGP, is detected in all tissues including red cells, lymphocytes and cultured fibroblasts (at protein level). The catalytic activity of PGP is 2-phosphoglycolate + H2O = glycolate + phosphate. The highest activities occur in skeletal muscle and cardiac muscle. Recombinant human PGP protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques. Plays a role in regulating glucose, lipid and energy metabolism
Product Categories/Family for PGP active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
34,006 Da
NCBI Official Full Name
phosphoglycolate phosphatase
NCBI Official Synonym Full Names
phosphoglycolate phosphatase
NCBI Official Symbol
PGP
NCBI Official Synonym Symbols
PGPase
NCBI Protein Information
phosphoglycolate phosphatase
UniProt Protein Name
Phosphoglycolate phosphatase
Protein Family
UniProt Gene Name
PGP
UniProt Synonym Gene Names
PGP; PGPase
UniProt Entry Name
PGP_HUMAN
Uniprot Description
PGP: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein type: Carbohydrate Metabolism - glyoxylate and dicarboxylate; EC 3.1.3.18; Phosphatase (non-protein); EC 3.1.3.48
Chromosomal Location of Human Ortholog: 16p13.3
Molecular Function: phosphoglycolate phosphatase activity; magnesium ion binding; protein tyrosine phosphatase activity
Biological Process: dephosphorylation; carbohydrate metabolic process
Research Articles on PGP
Similar Products
Product Notes
The PGP pgp (Catalog #AAA849817) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSHMAAAEA GGDDARCVRL SAERAQALLA DVDTLLFDCD GVLWRGETAV PGAPEALRAL RARGKRLGFI TNNSSKTRaa YAEKLRRLGF GGPAGPGASL EVFGTAYCTA LYLRQRLAGA PAPKAYVLGS PALAAELEAV GVASVGVGPE PLQGEGPGDW LHAPLEPDVR AVVVGFDPHF SYMKLTKALR YLQQPGCLLV GTNMDNRLPL ENGRFIAGTG CLVRAVEMaa QRQADIIGKP SRFIFDCVSQ EYGINPERTV MVGDRLDTDI LLGATCGLKT ILTLTGVSTL GDVKNNQESD CVSKKKMVPD FYVDSIADLL PALQG. It is sometimes possible for the material contained within the vial of "PGP, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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