Carbonic Anhydrase XIV/CA14 Recombinant Protein | CA14 recombinant protein

Carbonic Anhydrase XIV/CA14; Human Recombinant

Cat. Num. AAA8400682

• Gene Names: CA14; CAXiV
• Purity: >85% by SDS-PAGE
• Synonyms: Carbonic Anhydrase XIV/CA14; Human Recombinant; Carbonic anhydrase 14; CAXiV; CA14 recombinant protein

• Host: E Coli
• Specificity: Zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide.
• Purity/Purification: >85% by SDS-PAGE
• Form/Format: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 0.15 M NaCl; 10% glycerol; 1mM DTT
• Sequence Positions: aa16-290

• Source: Human
• Activity (Specifications/test method): > 700pmol/min/ug
• Tag: N terminus His-Tag
• Unit Definition: One unit is is defined as the amount of enzyme that hydrolyze 1.0 pmole of 4-nitrophenyl acetate to 4-nitrophenol per minute at pH7.5 at 37 degree C.
• Preparation and Storage: Store at -20 degree C; Centrifuge the vial prior to opening.; Shipping: Gel Pack; Shelf Life: Est.~12 months; Country of Origin: USA

SDS-Page

Related Product Information for CA14 recombinant protein

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA14 is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles. Recombinant human CA14 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.

Product Categories/Family for CA14 recombinant protein

Web Categories; Proteins and Enzymes; Proteins and Enzymes (A-Z); Diabetes; Obesity & Metabolic Syndrome; Lipids Metabolism; Proteins-Enzymes; Neuroscience; Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 6912284
• NCBI GeneID: 23632
• NCBI Accession #: NP_036245.1
• NCBI GenBank Nucleotide #: NM_012113.1
• UniProt Accession #: Q9ULX7; Q5TB24; Q8NCF4
• Molecular Weight: 37,668 Da
• NCBI Official Full Name: carbonic anhydrase 14
• NCBI Official Synonym Full Names: carbonic anhydrase XIV
• NCBI Official Symbol: CA14
• NCBI Official Synonym Symbols: CAXiV
• NCBI Protein Information: carbonic anhydrase 14; CA-XIV; carbonic dehydratase; carbonate dehydratase XIV
• UniProt Protein Name: Carbonic anhydrase 14
• Protein Family: Carbonic anhydrase
• UniProt Gene Name: CA14
• UniProt Synonym Gene Names: CA-XIV
• UniProt Entry Name: CAH14_HUMAN

NCBI Description

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles. [provided by RefSeq, Jul 2008]

Uniprot Description

CA14: Reversible hydration of carbon dioxide. Belongs to the alpha-carbonic anhydrase family.

Protein type: Lyase; EC 4.2.1.1; Membrane protein, integral; Energy Metabolism - nitrogen

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: integral to membrane; plasma membrane

Molecular Function: carbonate dehydratase activity; metal ion binding

Biological Process: bicarbonate transport