Typical Testing Data/Standard Curve (for reference only)
Succinate Dehydrogenase Assay Kit | OOM_0569 assay kit
Succinate Dehydrogenase Activity Colorimetric Assay Kit
Synonyms
Succinate Dehydrogenase; Succinate Dehydrogenase Activity Colorimetric Assay Kit; Succinate-Coenzyme Q Reductase Activity Colorimetric Assay Kit; Complex II Activity Colorimetric Assay Kit; OOM_0569 assay kit
Sequence Length
597
Application Notes
Measurement of Succinate Dehydrogenase Activity in various tissues/cells.
Analysis of citric acid cycle
Analysis of citric acid cycle
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Shelf Life: 12 months
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for OOM_0569 assay kit
Background/Introduction: Succinate Dehydrogenase (SDH) (EC 1.3.5.1) or succinate-coenzyme Q reductase (SQR) or respiratory complex II is an enzyme complex, which is bound to the inner mitochondrial membrane. SDH participates in both the citric acid cycle and electron transport chain. In mammals and many bacteria, SDH consists of 2 hydrophilic subunits, SDHA (flavoprotein) and SDHB (iron-sulfur protein) and 2 hydrophobic membrane anchor subunits: SDHC and SDHD. SDH oxidizes succinate to fumarate and transfers the electrons to ubiquinone. SDH deficiency in humans leads to a variety of phenotypes including Leigh syndrome, a neurometabolic disorder, tumor formation, and myopathy. Recent studies show that SDH can prevent the generation of ROS (reactive oxygen species); therefore, measurement of succinate dehydrogenase activity has wide applications. Succinate Dehydrogenase Activity Assay kit is rapid, simple and high-throughput adaptable. In this assay, Succinate dehydrogenase converts succinate to fumarate, and transfers the electron to an artificial electron acceptor (Probe), which changes the color from blue to a colorless product (depending upon the sample enzymatic activity). This assay kit can detect less than 0.1mU Succinate Dehydrogenase Activity in a variety of samples.
Product Categories/Family for OOM_0569 assay kit
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
65,695 Da
NCBI Official Full Name
succinate dehydrogenase
UniProt Protein Name
Succinate dehydrogenase flavoprotein subunit
Protein Family
UniProt Gene Name
OOM_0569
UniProt Entry Name
I2AY40_FRANT
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Product Notes
The Succinate Dehydrogenase oom_0569 (Catalog #AAA841500) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. Measurement of Succinate Dehydrogenase Activity in various tissues/cells. Analysis of citric acid cycle. Researchers should empirically determine the suitability of the Succinate Dehydrogenase oom_0569 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Succinate Dehydrogenase, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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