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Western Blot (WB)
(Western Blot analysis of various cells using Cleaved-Caspase-3 p17 (D175) Polyclonal Antibody at dilution of 1:1000.)
Apoptosis Antibody Kit
Apoptosis Antibody Sampler Kit (Mouse Preferred)
Applications
Western Blot
Synonyms
Apoptosis; Apoptosis Antibody Sampler Kit (Mouse Preferred); Apoptosis antibody kit
Applicable Applications for Apoptosis antibody kit
Western Blot (WB)
Western Blot (WB)
(Western Blot analysis of various cells using Cleaved-Caspase-3 p17 (D175) Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western Blot analysis of various cells using Cleaved-Caspase-3 p17 (D175) Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western Blot analysis of KB, MCF7 cells using Caspase-3 Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western Blot analysis of KB, MCF7 cells using Caspase-3 Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western Blot analysis of 3T3 cells with Caspase-8 Polyclonal Antibody.)
Western Blot (WB)
(Western Blot analysis of 3T3 cells with Caspase-8 Polyclonal Antibody.)
Western Blot (WB)
(Western Blot analysis of NIH/3T3 cell using CASP12 Polyclonal Antibody at dilution of 1:700)
Western Blot (WB)
(Western Blot analysis of NIH/3T3 cell using CASP12 Polyclonal Antibody at dilution of 1:700)
Western Blot (WB)
(Western Blot analysis of various cells using Caspase-9 Polyclonal Antibody at dilution of 1:500.)
Western Blot (WB)
(Western Blot analysis of various cells using Caspase-9 Polyclonal Antibody at dilution of 1:500.)
Western Blot (WB)
(Western Blot analysis of Rat musle using PARP-1 Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western Blot analysis of Rat musle using PARP-1 Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western Blot analysis of A549 cells using Cleaved-PARP-1 (D214) Polyclonal Antibody at dilution of 1:2000.)
Western Blot (WB)
(Western Blot analysis of A549 cells using Cleaved-PARP-1 (D214) Polyclonal Antibody at dilution of 1:2000.)
Related Product Information for Apoptosis antibody kit
Background: Apoptosis is a regulated physiological process leading to cell death. Caspases, a family of cysteine acid proteases, are central regulators of apoptosis. Initiator caspases (including 8, 9, 10 and 12) are closely coupled to proapoptotic signals. Once activated, these caspases cleave and activate downstream effector caspases (including 3, 6 and 7), which in turn cleave cytoskeletal and nuclear proteins like PARP, alpha-fodrin, DFF and lamin A, and induce apoptosis. Cytochrome c released from mitochondria is coupled to the activation of caspase-9, a key initiator caspase. Proapoptotic stimuli include the FasL, TNF-alpha, DNA damage and ER stress. Fas and TNFR activate caspases 8 and 10, DNA damage leads to the activation of caspase-9 and ER stress leads to the calcium-mediated activation of caspase-12. The inhibitor of apoptosis protein (IAP) family includes XIAP and survivin and functions by binding and inhibiting several caspases. Smac/Diablo, a mitochondrial protein, is released into the cytosol upon mitochondrial stress and competes with caspases for binding of IAPs. The interaction of Smac/Diablo with IAPs relieves the inhibitory effects of the IAPs on caspases.
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Product Notes
The Apoptosis (Catalog #AAA2550133) is an Antibody Kit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Apoptosis can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the Apoptosis for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Apoptosis, Antibody Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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