Rabbit MAP1B Polyclonal Antibody | anti-MAP1B antibody

MAP1B Polyclonal Antibody

Cat. Num. AAA2526789

• Gene Names: MAP1B; MAP5; FUTSCH; PPP1R102
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Immunohistochemistry
• Purity: Antigen affinity purification
• Synonyms: MAP1B; Polyclonal Antibody; MAP1B Polyclonal Antibody; MAP5; FUTSCH; anti-MAP1B antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen affinity purification
• Concentration: 2.2mg/mL (varies by lot)
• Sequence Length: 2468

• Applicable Applications for anti-MAP1B antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Application Notes: IHC: 1:50-1:200
• Immunogen: Synthetic peptide of human MAP1B
• Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
• Preparation and Storage: Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human brain tissue using MAP1B Polyclonal Antibody at dilution 1:60)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human lung cancer tissue using MAP1B Polyclonal Antibody at dilution 1:60)

Related Product Information for anti-MAP1B antibody

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system.

NCBI and Uniprot Product Information

• NCBI GI #: 153945728
• NCBI GeneID: 4131
• NCBI Accession #: NP_005900.2
• NCBI GenBank Nucleotide #: NM_005909.3
• Molecular Weight: 270,634 Da
• NCBI Official Full Name: microtubule-associated protein 1B
• NCBI Official Synonym Full Names: microtubule-associated protein 1B
• NCBI Official Symbol: MAP1B
• NCBI Official Synonym Symbols: MAP5; FUTSCH; PPP1R102
• NCBI Protein Information: microtubule-associated protein 1B; MAP-1B; protein phosphatase 1, regulatory subunit 102
• UniProt Protein Name: Microtubule-associated protein 1B
• Protein Family: Methionine aminopeptidase
• UniProt Gene Name: MAP1B
• UniProt Synonym Gene Names: MAP-1B
• UniProt Entry Name: MAP1B_HUMAN

NCBI Description

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system. [provided by RefSeq, Jul 2008]

Uniprot Description

MAP1B: the function of brain MAPS is essentially unknown. Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B Binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 5q13

Cellular Component: microtubule; microtubule associated complex; postsynaptic density; cytoplasm; dendritic spine; plasma membrane; cytosol; cell junction

Molecular Function: protein binding; microtubule binding; structural molecule activity

Biological Process: negative regulation of intracellular transport; axon extension; positive regulation of axon extension; dendrite development; cellular process; microtubule bundle formation; mitochondrion transport along microtubule