Rabbit DRAXIN Polyclonal Antibody | anti-DRAXIN antibody

Rabbit anti-Homo sapiens (Human) DRAXIN Polyclonal Antibody

• Gene Names: DRAXIN; UNQ3119; neucrin; AGPA3119; C1orf187
• Reactivity: Homo sapiens (Human)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: DRAXIN; Polyclonal Antibody; Rabbit anti-Homo sapiens (Human) DRAXIN Polyclonal Antibody; DRAXIN Antibody; Draxin; Dorsal inhibitory axon guidance protein; Dorsal repulsive axon guidance protein; Neucrin); C1orf187; anti-DRAXIN antibody

• Host: Rabbit
• Reactivity: Homo sapiens (Human)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-DRAXIN antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Homo sapiens DRAXIN protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 86990448
• NCBI GeneID: 374946
• NCBI Accession #: BAG80561
• NCBI GenBank Nucleotide #: NM_198545.3
• UniProt Accession #: Q8NBI3; Q5SNX0; Q6UWK8; B6EV15
• Molecular Weight: 38,650 Da
• NCBI Official Full Name: draxin
• NCBI Official Synonym Full Names: dorsal inhibitory axon guidance protein
• NCBI Official Symbol: DRAXIN
• NCBI Official Synonym Symbols: UNQ3119; neucrin; AGPA3119; C1orf187
• NCBI Protein Information: draxin; dorsal repulsive axon guidance protein; dorsal inhibitory axon guidance protein; neural tissue-specific cysteine-rich protein
• UniProt Protein Name: Draxin
• Protein Family: Draxin
• UniProt Gene Name: DRAXIN
• UniProt Entry Name: DRAXI_HUMAN

Uniprot Description

DRAXIN: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta- catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. Belongs to the draxin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1p36.22

Cellular Component: extracellular region

Biological Process: dorsal spinal cord development; axon guidance; Wnt receptor signaling pathway; forebrain development; commissural neuron differentiation in the spinal cord; negative regulation of neuron apoptosis; negative regulation of axon extension