SDS-Page
(Recombinant KDM6C protein gel. KDM6C protein was run on an 8% SDS-PAGE gel and stained with Coomassie Blue.)
KDM6C recombinant protein
Recombinant KDM6C protein
Gene Names
UTY; UTY1; KDM6C; KDM6AL
Purity
The recombinant protein is >70% pure by SDS-PAGE.
Synonyms
KDM6C; Recombinant KDM6C protein; Histone demethylase UTY;; KDM6C recombinant protein
Host
Baculovirus
Purity/Purification
The recombinant protein is >70% pure by SDS-PAGE.
Form/Format
Recombinant KDM6C protein is supplied in 25mM HEPES pH7.5, 300mM NaCl, 5% glycerol, 0.04% Triton X-100, 0.2mM TCEP.
Protein Species
Human
Tag
DYKDDDDK-Tag
Notes
This product was manufactured as described in Protein Details. Where possible, We has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for a given product is shown on the lot-specific Technical Data Sheet.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
Shipping Temp: Dry Ice
SDS-Page
(Recombinant KDM6C protein gel. KDM6C protein was run on an 8% SDS-PAGE gel and stained with Coomassie Blue.)
SDS-Page
(Recombinant KDM6C protein gel. KDM6C protein was run on an 8% SDS-PAGE gel and stained with Coomassie Blue.)
Related Product Information for KDM6C recombinant protein
Short Description: Recombinant KDM6C (accession number NP_009056.3) was expressed in Sf9 cells as full-length protein and contains an N-terminal DYKDDDDK-Tag with an observed molecular weight of 152.9 kDa. The recombinant protein is >70% pure by SDS-PAGE. It is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.
Background: KDM6C (lysine (K)-specific demethylase 6C), also known as UTY (Ubiquitously Transcribed Tetratricopeptide Repeat Containing, Y-Linked) is a KDM6 subfamily member that catalyzes demethylation of N-methylated histone 3 lysine 27 (H3K27), a mark important for transcriptional repression. The activity of UTY (KDM6C) is much weaker than KDM6A and KDM6B, due to point substitutions involved in substrate binding.
Background: KDM6C (lysine (K)-specific demethylase 6C), also known as UTY (Ubiquitously Transcribed Tetratricopeptide Repeat Containing, Y-Linked) is a KDM6 subfamily member that catalyzes demethylation of N-methylated histone 3 lysine 27 (H3K27), a mark important for transcriptional repression. The activity of UTY (KDM6C) is much weaker than KDM6A and KDM6B, due to point substitutions involved in substrate binding.
Product Categories/Family for KDM6C recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
134,762 Da
NCBI Official Full Name
histone demethylase UTY isoform 3
NCBI Official Synonym Full Names
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
NCBI Official Symbol
UTY
NCBI Official Synonym Symbols
UTY1; KDM6C; KDM6AL
NCBI Protein Information
histone demethylase UTY
UniProt Protein Name
Histone demethylase UTY
UniProt Gene Name
UTY
UniProt Entry Name
UTY_HUMAN
NCBI Description
This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. The encoded protein is also a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. A large number of alternatively spliced transcripts have been observed for this gene, but the full length nature of some of these variants has not been determined. [provided by RefSeq, Apr 2012]
Research Articles on KDM6C
Similar Products
Product Notes
The KDM6C uty (Catalog #AAA388277) is a Recombinant Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "KDM6C, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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