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Western Blot (WB) (Western blot analysis of UTY Antibody (C-term) in mouse brain tissue lysates (35ug/lane). UTY (arrow) was detected using the purified Pab.)

Rabbit anti-Human UTY Polyclonal Antibody | anti-UTY antibody

UTY Antibody (C-term)

Gene Names
UTY; UTY1; KDM6AL
Reactivity
Human
Applications
Western Blot, ELISA, Immunofluorescence, Flow Cytometry, Functional Assay
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
UTY; Polyclonal Antibody; UTY Antibody (C-term); Histone demethylase UTY; 11411-; Ubiquitously-transcribed TPR protein on the Y chromosome; Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein; KDM6C; anti-UTY antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This UTY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1247-1276 amino acids from the C-terminal region of human UTY.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.45 (varies by lot)
Sequence Positions
1247-1276
Sequence Length
1,211
Applicable Applications for anti-UTY antibody
Western Blot (WB), ELISA (EIA), Immunofluorescence (IF), Flow Cytometry (FC/FACS)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of UTY Antibody (C-term) in mouse brain tissue lysates (35ug/lane). UTY (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of UTY Antibody (C-term) in mouse brain tissue lysates (35ug/lane). UTY (arrow) was detected using the purified Pab.)

Flow Cytometry (FC/FACS)

(UTY Antibody (C-term) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (UTY Antibody (C-term) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Immunofluorescence (IF)

(Confocal immunofluorescent analysis of UTY Antibody (C-term) with MDA-MB231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).)

Immunofluorescence (IF) (Confocal immunofluorescent analysis of UTY Antibody (C-term) with MDA-MB231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).)
Related Product Information for anti-UTY antibody
UTY encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. This protein is a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts.
References
Russo,P., et.al., Arterioscler. Thromb. Vasc. Biol. 28 (8), 1569-1574 (2008)
Gerrard,D.T. et.al., Mol. Biol. Evol. 22 (6), 1423-1432 (2005)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
149548
NCBI Official Full Name
histone demethylase UTY isoform 7
NCBI Official Synonym Full Names
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
NCBI Official Symbol
UTY
NCBI Official Synonym Symbols
UTY1; KDM6AL
NCBI Protein Information
histone demethylase UTY
UniProt Protein Name
Histone demethylase UTY
Protein Family
UniProt Gene Name
UTY
UniProt Synonym Gene Names
KDM6C
UniProt Entry Name
UTY_HUMAN

NCBI Description

This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. The encoded protein is also a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. A large number of alternatively spliced transcripts have been observed for this gene, but the full length nature of some of these variants has not been determined. [provided by RefSeq, Apr 2012]

Uniprot Description

UTY: Histone demethylase. Belongs to the UTX family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell surface; Oxidoreductase; EC 1.14.11.-

Chromosomal Location of Human Ortholog: Yq11

Cellular Component: nucleus

Molecular Function: dioxygenase activity; metal ion binding

Biological Process: regulation of gene expression

Research Articles on UTY

Similar Products

Product Notes

The UTY uty (Catalog #AAA9213423) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1247-1276. The UTY Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's UTY can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunofluorescence (IF), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the UTY uty for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UTY, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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