SDS-Page
(Recombinant KDM1B / LSD2 protein gel. Recombinant KDM1B / LSD2 run on an 8% SDS-PAGE gel and stained with Coomassie blue.)
KDM1B/LSD2 recombinant protein
Recombinant KDM1B/LSD2 protein
Purity
The recombinant protein is >92% pure by SDS-PAGE.
Synonyms
KDM1B/LSD2; Recombinant KDM1B/LSD2 protein; Lysine Demethylase 1B; Flavin-Containing Amine Oxidase Domain-Containing Protein 1; KDM1B/LSD2 recombinant protein
Host
Baculovirus
Purity/Purification
The recombinant protein is >92% pure by SDS-PAGE.
Form/Format
Full length recombinant KDM1B/LSD2 protein is supplied in 25mM Tris, pH8, 300mM NaCl, 10% glycerol, and 0.5mM TCEP.
Protein Species
Human
Tag
GST-Tag
Notes
This product was manufactured as described in Protein Details. Where possible, We has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for a given product is shown on the lot-specific Technical Data Sheet.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
Shipping Temp: Dry Ice
SDS-Page
(Recombinant KDM1B / LSD2 protein gel. Recombinant KDM1B / LSD2 run on an 8% SDS-PAGE gel and stained with Coomassie blue.)
SDS-Page
(Recombinant KDM1B / LSD2 protein gel. Recombinant KDM1B / LSD2 run on an 8% SDS-PAGE gel and stained with Coomassie blue.)
Related Product Information for KDM1B/LSD2 recombinant protein
Short Description: Full-length Recombinant KDM1B/LSD2 (accession number XM_005248926.1) was expressed in was expressed in Sf9 cells and contains an N-terminal GST-Tag with an observed molecular weight of 116 kDa. The recombinant protein is >92% pure by SDS-PAGE. It is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.
Background: KDM1B/LSD2 (Lysine (K)-Specific Demethylase 1B/Lysine-Specific Histone Demethylase 2) is a histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4 (by similarity).
Background: KDM1B/LSD2 (Lysine (K)-Specific Demethylase 1B/Lysine-Specific Histone Demethylase 2) is a histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4 (by similarity).
Product Categories/Family for KDM1B/LSD2 recombinant protein
NCBI and Uniprot Product Information
Molecular Weight
Molecular weight of 116kDa
Similar Products
Product Notes
The KDM1B/LSD2 (Catalog #AAA388190) is a Recombinant Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "KDM1B/LSD2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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