Tax1 Recombinant Protein | TAX1BP3 recombinant protein
Recombinant Human Tax1 Binding Protein 3
Gene Names
TAX1BP3; TIP-1
Purity
Greater than 95% as determined by SDS-PAGE.
Synonyms
Tax1; Recombinant Human Tax1 Binding Protein 3; TAX1BP3 Human; Tax1 Binding Protein 3 Human Recombinant; Tax1 (human T-cell leukemia virus type I) binding protein 3; TIP-1; Glutaminase-interacting protein 3; Tax interaction protein 1; TAX1BP3 recombinant protein
Host
E Coli
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Form/Format
TAX1BP3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 1mM DTT, 0.1M NaCl and 20% glycerol.
Sterile Filtered colorless solution.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MSYIPGQPVT AVVQRVEIHK LRQGENLILG FSIGGGIDQD PSQNPFSEDK TDKGIYVTRV SEGGPAEIAG LQIGDKIMQV NGWDMTMVTH DQARKRLTKR SEEVVRLLVT RQSLQKAVQQ SMLS.
Sequence Length
98
Related Product Information for TAX1BP3 recombinant protein
Description: TAX1BP3 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 144 amino acids (1-124 a.a.) and having a molecular mass of 15.8kDa.TAX1BP3 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: TAX1BP3 holds one PDZ domain, which uses for interactions with other proteins like the interaction with the C-terminus of Rhotekin that facilitates Rho-mediated activation of the FOS serum response element. In addition, PDZ domain interacts with beta-catenin to inhibit the transcriptional activity of beta-catenin. TAX1BP3 exists in several cell lines, such as HeLa, and is expressed in small quantities in peripheral blood leukocytes.
Introduction: TAX1BP3 holds one PDZ domain, which uses for interactions with other proteins like the interaction with the C-terminus of Rhotekin that facilitates Rho-mediated activation of the FOS serum response element. In addition, PDZ domain interacts with beta-catenin to inhibit the transcriptional activity of beta-catenin. TAX1BP3 exists in several cell lines, such as HeLa, and is expressed in small quantities in peripheral blood leukocytes.
Product Categories/Family for TAX1BP3 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
13,735 Da
NCBI Official Full Name
tax1-binding protein 3 isoform 2
NCBI Official Synonym Full Names
Tax1 (human T-cell leukemia virus type I) binding protein 3
NCBI Official Symbol
TAX1BP3
NCBI Official Synonym Symbols
TIP-1
NCBI Protein Information
tax1-binding protein 3; TAX1BP3; Tax interaction protein 1; glutaminase-interacting protein 3; tax-interacting protein 1
UniProt Protein Name
Tax1-binding protein 3
Protein Family
UniProt Gene Name
TAX1BP3
UniProt Synonym Gene Names
TIP-1
UniProt Entry Name
TX1B3_HUMAN
Uniprot Description
TAX1BP3: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.
Protein type: Cell cycle regulation; Adaptor/scaffold
Chromosomal Location of Human Ortholog: 17p13
Cellular Component: cytoplasm; plasma membrane; nucleus; actin cytoskeleton
Molecular Function: protein C-terminus binding; protein binding; beta-catenin binding
Biological Process: negative regulation of cell proliferation; Wnt receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; Rho protein signal transduction
Research Articles on TAX1BP3
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Product Notes
The TAX1BP3 tax1bp3 (Catalog #AAA145162) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MSYIPGQPVT AVVQRVEIHK LRQGENLILG FSIGGGIDQD PSQNPFSEDK TDKGIYVTRV SEGGPAEIAG LQIGDKIMQV NGWDMTMVTH DQARKRLTKR SEEVVRLLVT RQSLQKAVQQ SMLS. It is sometimes possible for the material contained within the vial of "Tax1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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