SDS-Page
(Recombinant SIRT6 protein run on an 10% SDS-PAGE gel and stained with Coomassie Blue.)
SIRT6 recombinant protein
Recombinant SIRT6 protein
Purity
The recombinant protein is > 65% pure by SDS-PAGE.
Synonyms
SIRT6; Recombinant SIRT6 protein; Sirtuin 6; Regulatory Protein SIR2 Homolog; SIR2-Like Protein 6; SIRT-6; SIRT6 recombinant protein
Host
E Coli
Purity/Purification
The recombinant protein is > 65% pure by SDS-PAGE.
Form/Format
Full length recombinant SIRT6 protein is supplied in 25mM Tris pH8.0, 300mM NaCl, 0.04% Triton X-100, 5% glycerol. Please refer to product insert upon arrival for lot-specific concentration.
Protein Species
Human
Tag
GST-Tag
Notes
This product was manufactured as described in Protein Details. Where possible, We has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for a given product is shown on the lot-specific Technical Data Sheet.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
Shipping Temp: Dry Ice
SDS-Page
(Recombinant SIRT6 protein run on an 10% SDS-PAGE gel and stained with Coomassie Blue.)
SDS-Page
(Recombinant SIRT6 protein run on an 10% SDS-PAGE gel and stained with Coomassie Blue.)
Related Product Information for SIRT6 recombinant protein
Short Description: Recombinant human SIRT6 was expressed in E Coli as the full-length protein (accession number NM_016539) with an N-terminal GST-Tag. The molecular weight of the protein is ~65 kDa. The recombinant protein is > 65% pure by SDS-PAGE. It is suitable for use in histone deacetylase (HDAC) assays, in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.
Background: SIRT6 (Sir2 homologue 6) is an NAD+ dependant histone deacetylase (HDAC) related to SIRT1 and to the yeast Sir2 protein. SIRT6, originally identified as a tubulin deacetylase, was recently found to be able to deacetylate histone H3 acetylated at lysine 9.In vivo, acetylation is controlled by the antagonistic activities of histone acetyltransferases (HATs) and histone deacetylases (HDACs). The HDACs are grouped into four classes, on the basis of similarity to yeast counterparts: class I (HDAC1, HDAC2, HDAC3 and HDAC8), class II (HDAC4, HDAC5, HDAC6, HDAC7, HDAC9 and 10), class III (SIRT1-7) and class IV (HDAC11).
Background: SIRT6 (Sir2 homologue 6) is an NAD+ dependant histone deacetylase (HDAC) related to SIRT1 and to the yeast Sir2 protein. SIRT6, originally identified as a tubulin deacetylase, was recently found to be able to deacetylate histone H3 acetylated at lysine 9.In vivo, acetylation is controlled by the antagonistic activities of histone acetyltransferases (HATs) and histone deacetylases (HDACs). The HDACs are grouped into four classes, on the basis of similarity to yeast counterparts: class I (HDAC1, HDAC2, HDAC3 and HDAC8), class II (HDAC4, HDAC5, HDAC6, HDAC7, HDAC9 and 10), class III (SIRT1-7) and class IV (HDAC11).
Product Categories/Family for SIRT6 recombinant protein
NCBI and Uniprot Product Information
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Molecular weight of the protein is ~65 kDa
Protein Family
Similar Products
Product Notes
The SIRT6 (Catalog #AAA388236) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SIRT6, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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