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36 results for " PI3K Akt Signaling Pathway" - showing 1-36

Fibronectin (FN1), Active Protein (Cat# AAA7115172)

Full Name
Recombinant Human Fibronectin (FN1), Partial
Gene Names
FN1; FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; SMDCF
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
$135/0.01 mg | $205/0.05 mg | $825/5x0.05 mg

B-Lymphocyte Antigen CD19 (CD19), Active Protein (Cat# AAA7115103)

Full Name
Recombinant Human B-Lymphocyte Antigen CD19 (CD19), Partial
Gene Names
CD19; B4; CVID3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
$250/0.01 mg | $535/0.05 mg | $2,240/5x0.05 mg
Dot Blot (DB) (Dot blot analysis of anti-Phospho-INSR-pY1185 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.)

Phospho-INSR (Y1185), Polyclonal Antibody (Cat# AAA9204291)

Full Name
Phospho-INSR (Y1185) Antibody
Gene Names
INSR; HHF5; CD220
Reactivity
Human (Predicted Reactivity: Bovine, Mouse, Rat, Xenopus, Drosophila)
Applications
DB, EIA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$415/0.4 mL | $185/0.08 mL | $1,625/5x0.4 mL
Testing Data (PI-103 is a potent, cell-permeable, ATP-competitive PI3K family members inhibitor with IC50 of 2, 8, 20, 26, 48, 83, 88, 150 nM for DNA-PK, p110alpha, mTORC1, PI3-KC2beta, p110delta, mTORC2, p110beta, and p110gamma, respectively. It shows little activity against a wide array of protein kinases at 10 mM. It blocks glioma proliferation by blocking the PI 3-K/Akt pathway in vitro and in vivo. PI-103 was essentially cytostatic for cell lines and induced cell cycle arrest in the G1 phase. In blast cells, PI-103 inhibited leukemic proliferation, the clonogenicity of leukemic progenitors and induced mitochondrial apoptosis, especially in the compartment containing leukemic stem cells. PI-103 had additive proapoptotic effects with etoposide in blast cells and in immature leukemic cells. [1][2][3])

PI-103, Inhibitor (Cat# AAA8506504)

Full Name
PI-103
Purity
>99%
Pricing
$295/5 mg | $1,255/5x5 mg
Western Blot (WB) (Western blot analysis of extracts from NIH/3T3-Src, using Phospho-P85 alpha(Tyr508) Antibody. Lane1 was treated with phospho-blocking peptide, Lane2 was treated with non-phospho-blocking peptide.)

PI3K p85 alpha, Polyclonal Antibody (Cat# AAA9613173)

Full Name
Phospho-PI3K p85 alpha (Tyr508) Antibody
Gene Names
PIK3R1; p85; AGM7; GRB1; p85-ALPHA
Reactivity
Human, Mouse, Rat
Predicted Reactivity: Zebrafish (92%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (83%)
Applications
WB, IF, ICC, EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL
Western Blot (WB) (Western blot analysis of extracts from Pc12, using P85 alpha Antibody. The lane on the left was treated with blocking peptide.)

PI3K p85 alpha, Polyclonal Antibody (Cat# AAA9613380)

Full Name
PI3K p85 alpha Antibody
Gene Names
PIK3R1; p85; AGM7; GRB1; p85-ALPHA
Reactivity
Human, Mouse, Rat
Predicted Reactivity: Zebrafish (92%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (83%)
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Pricing
$245/0.05 mL | $305/0.1 mL | $365/0.2 mL | $1,495/5x0.2 mL

Ethyl gallate, Inhibitor (Cat# AAA579726)

Full Name
Ethyl gallate
Purity
99.6%
Pricing
$195/100 mg | $215/1 g | $195/1 mL (in DMSO) | $690/5x1 g

GPER1 / G-Protein Coupled Estrogen Receptor 1, Recombinant Protein (Cat# AAA2902279)

Full Name
Human GPER1 / G-Protein Coupled Estrogen Receptor 1 Recombinant Protein
Gene Names
GPER1; mER; CEPR; GPER; DRY12; FEG-1; GPR30; LERGU; LyGPR; CMKRL2; LERGU2; GPCR-Br
Applications
EIA, WB, AP
Purity
>95% by SDS-PAGE
Western Blot (WB) (Western blot analysis of extracts from NIH-3T3 cells, using P85 alpha Antibody. The lane on the left was treated with blocking peptide.)

PI3K p85 alpha, Polyclonal Antibody (Cat# AAA9613378)

Full Name
PI3K p85 alpha Antibody
Gene Names
PIK3R1; p85; AGM7; GRB1; p85-ALPHA
Reactivity
Human, Mouse, Rat
Predicted Reactivity: Zebrafish (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (100%)
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Pricing
$245/0.05 mL | $305/0.1 mL | $365/0.2 mL | $1,495/5x0.2 mL
Western Blot (WB) (Western blot analysis of PIK3CA in lysates of Jurkat  , using PIK3CA Antibody(AF4669).)

PIK3CA, Polyclonal Antibody (Cat# AAA9613377)

Full Name
PIK3CA Antibody
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; p110-alpha
Reactivity
Human, Mouse, Rat
Predicted Reactivity: Pig (100%), Zebrafish (92%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (83%)
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Pricing
$245/0.05 mL | $305/0.1 mL | $365/0.2 mL | $1,495/5x0.2 mL
Western Blot (WB) (Western blot analysis of extracts from Jurkat  , using Phospho-PIK3CA(Tyr317) Antibody. Lane1 was treated with phospho-blocking peptide, Lane2 was treated with non-phospho-blocking peptide.)

PIK3CA, Polyclonal Antibody (Cat# AAA9613170)

Full Name
Phospho-PIK3CA (Tyr317) Antibody
Gene Names
PIK3CA; MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; p110-alpha
Reactivity
Human, Mouse, Rat
Predicted Reactivity: Pig (100%), Zebrafish (92%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (83%)
Applications
WB, EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL
Western Blot (WB) (Western blot analysis of extracts from NIH/3T3-Src, using Phospho-P85 alpha(Tyr580) Antibody. Lane1 was treated with phospho-blocking peptide, Lane2 was treated with non-phospho-blocking peptide.)

PI3K p85 alpha, Polyclonal Antibody (Cat# AAA9613171)

Full Name
Phospho-PI3K p85 alpha (Tyr580) Antibody
Gene Names
PIK3R1; p85; AGM7; GRB1; p85-ALPHA
Reactivity
Human, Mouse, Rat
Predicted Reactivity: Zebrafish (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (100%)
Applications
WB, EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL

INSR / Insulin Receptor, Recombinant Protein (Cat# AAA2901969)

Full Name
Human INSR / Insulin Receptor Recombinant Protein
Gene Names
INSR; HHF5; CD220
Applications
EIA, WB, AP
Purity
>95% by SDS-PAGE

PIM2 / Serine/Threonine-Protein Kinase Pim-2, Recombinant Protein (Cat# AAA2903449)

Full Name
Human PIM2 / Serine/Threonine-Protein Kinase Pim-2 Recombinant Protein
Applications
EIA, WB, AP
Purity
>95% by SDS-PAGE

8-Prenylkaempferol, Inhibitor (Cat# AAA5760092)

Full Name
8-Prenylkaempferol
Purity
98.00%
Pricing
$360/1 mg | $1,325/5x1 mg
Western Blot (WB) (Western blot analysis of P85 alpha in lysates of A431  , using P85 alpha Antibody(AF4671).)

PI3K p85 alpha, Polyclonal Antibody (Cat# AAA9613379)

Full Name
PI3K p85 alpha Antibody
Gene Names
PIK3R1; p85; AGM7; GRB1; p85-ALPHA
Reactivity
Human, Mouse, Rat
Predicted Reactivity: Zebrafish (83%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (83%)
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Pricing
$245/0.05 mL | $305/0.1 mL | $365/0.2 mL | $1,495/5x0.2 mL

ULBP2 / NKG2D Ligand 2, Recombinant Protein (Cat# AAA2903273)

Full Name
Human ULBP2 / NKG2D Ligand 2 Recombinant Protein
Gene Names
ULBP2; N2DL2; RAET1H; RAET1L; NKG2DL2; ALCAN-alpha
Applications
EIA, WB, AP
Purity
>95% by SDS-PAGE
Western Blot (WB) (Western blot analysis of extracts from Mouse kidney, using Phospho-C/EBP alpha (Ser190) Antibody. The lane on the left was treated with blocking peptide.)

C/EBP alpha, Polyclonal Antibody (Cat# AAA9614038)

Full Name
Phospho-C/EBP alpha (Ser190) Antibody
Gene Names
CEBPA; CEBP; C/EBP-alpha
Reactivity
Human, Mouse, Rat
Applications
WB, EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL
Western Blot (WB) (Western blot analysis of extracts from NIH/3T3-Src, using Phospho-P85 alpha(Tyr452) Antibody. Lane1 was treated with phospho-blocking peptide, Lane2 was treated with non-phospho-blocking peptide.)

PI3K p85 alpha, Polyclonal Antibody (Cat# AAA9613172)

Full Name
Phospho-PI3K p85 alpha (Tyr452) Antibody
Gene Names
PIK3R1; p85; AGM7; GRB1; p85-ALPHA
Reactivity
Human, Mouse, Rat
Predicted Reactivity: Zebrafish (83%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (83%)
Applications
WB, EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL
Western Blot (WB) (Western blot analysis of extracts from Mouse brain, using C/EBP alpha Antibody. The lane on the left was treated with blocking peptide.)

C/EBP alpha, Polyclonal Antibody (Cat# AAA9613680)

Full Name
C/EBP alpha Antibody
Gene Names
CEBPA; CEBP; C/EBP-alpha
Reactivity
Human, Mouse, Rat
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB) (Western blot detection of Phospho-AKT (Ser473) in C6,3T3,Hela cell lysates using Phospho-AKT (Ser473) Rabbit mAb(1:1000 diluted).Predicted band size:56kDa.Observed band size:56kDa.)

AKT, Monoclonal Antibody (Cat# AAA4754090)

Full Name
Phospho-AKT (Ser473) Rabbit mAb
Gene Names
AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA
Reactivity
Human, Mouse, Rat
Applications
WB, IHC-P, IHC-F, ICC, IF
Purity
Affinity purified
Pricing
$440/0.1 mL | $1,530/5x0.1 mL

Polyporenic acid C, Inhibitor (Cat# AAA5759903)

Full Name
Polyporenic acid C
Purity
98.00%
Pricing
$360/1 mg | $800/5 mg | $3,310/5x5 mg

C/EBP alpha, Polyclonal Antibody (Cat# AAA9612727)

Full Name
Phospho-C/EBP alpha (Thr230) Antibody
Gene Names
CEBPA; CEBP; C/EBP-alpha
Reactivity
Human, Mouse, Rat
Applications
EIA
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Pricing
$310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL

PKC zeta, Polyclonal Antibody (Cat# AAA9630892)

Full Name
PKC zeta Antibody
Gene Names
PRKCZ; PKC2; PKC-ZETA
Reactivity
Human, Mouse, Rat
Applications
EIA, peptide
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Structure

Sonolisib, Inhibitor (Cat# AAA5755543)

Full Name
Sonolisib
Purity
98.00%
Pricing
$375/1 mg | $870/5 mg | $3,620/5x5 mg

Ganodermanondiol, Inhibitor (Cat# AAA5760399)

Full Name
Ganodermanondiol
Purity
98.00%
Pricing
$550/5 mg | $2,170/5x5 mg
Western Blot (WB) (Western blot analysis of extracts of various cell lines, using PHLPP2 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (RM00020).Exposure time: 180s.)

PHLPP2, Polyclonal Antibody (Cat# AAA9143200)

Full Name
PHLPP2 Rabbit pAb
Gene Names
PHLPP2; PHLPPL
Reactivity
Human, Mouse, Rat
Applications
WB, IF
Purity
Affinity purification
Pricing
$180/0.02 mL | $210/0.05 mL | $285/0.1 mL | $430/0.2 mL | $1,790/5x0.2 mL

Phospho-ATG13-Ser355, Polyclonal Antibody (Cat# AAA9143855)

Full Name
Phospho-ATG13-Ser355 Rabbit pAb
Gene Names
ATG13; KIAA0652; PARATARG8
Reactivity
Human, Mouse, Rat
Applications
WB
Purity
Affinity purification
Pricing
$180/0.02 mL | $250/0.05 mL | $350/0.1 mL | $525/0.2 mL | $2,210/5x0.2 mL
Structure

DMH-25, Inhibitor (Cat# AAA5759355)

Full Name
DMH-25
Purity
98.00%
Pricing
$270/1 mg | $415/5 mg | $565/10 mg | $915/25 mg | $3,845/5x25 mg

FAM83B, Polyclonal Antibody (Cat# AAA9629628)

Full Name
FAM83B Antibody
Gene Names
FAM83B; C6orf143
Reactivity
Human, Mouse
Applications
EIA, peptide
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB) (Western blot analysis of extracts of 293T cells, using Phospho-ULK1-S638 antibody at 1:1000 dilution.293T cells were treated by oligomycin (0.5 uM) at 37℃ for 30 minutes.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (RM00020).Exposure time: 180s.)

Phospho-ULK1-S638, Polyclonal Antibody (Cat# AAA9143902)

Full Name
Phospho-ULK1-S638 Rabbit pAb
Gene Names
ULK1; ATG1; ATG1A; UNC51; hATG1; Unc51.1
Reactivity
Human, Mouse
Applications
WB
Purity
Affinity purification
Pricing
$250/0.05 mL | $350/0.1 mL | $525/0.2 mL | $2,210/5x0.2 mL
Western Blot (WB) (Western blot analysis of extracts of various cell lines, using Phospho-ULK1-S467 antibody at 1:1000 dilution.HeLa and Jurkat cells were treated by Serum-starvation overnight at 37℃.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (RM00021).Exposure time: 180s.)

Phospho-ULK1-S467, Polyclonal Antibody (Cat# AAA9143932)

Full Name
Phospho-ULK1-S467 Rabbit pAb
Gene Names
ULK1; ATG1; ATG1A; UNC51; hATG1; Unc51.1
Reactivity
Human, Mouse
Applications
WB
Purity
Affinity purification
Pricing
$250/0.05 mL | $350/0.1 mL | $525/0.2 mL | $2,210/5x0.2 mL

GLTSCR2, Polyclonal Antibody (Cat# AAA9629605)

Full Name
GLTSCR2 Antibody
Gene Names
GLTSCR2; PICT1; PICT-1
Reactivity
Human
Applications
EIA, peptide
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL

Girdin, Polyclonal Antibody (Cat# AAA9630326)

Full Name
Girdin Antibody
Gene Names
CCDC88A; APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212
Reactivity
Human, Mouse
Applications
EIA, peptide
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Chemical Structure

AMG 511, Inhibitor (Cat# AAA5764654)

Full Name
AMG 511
Pricing
$240/1 mg | $330/5 mg | $505/10 mg | $970/25 mg | $1,385/50 mg | $515/1 mL (in DMSO) | $5,975/5x50 mg
Western Blot (WB) (Sample Data: Western blot using Affinity Purified Anti-Phospho-GSKalpha (Ser21) antibody to detect human GSK3A in various human derived 293T cell extracts. Cells were serum starved for 24 h. Lane 1: control, Lane 2: treated with IGF-1 (100 ng/ml) for 20 min, Lane 3: pre-treated with 10 uM LY294002 (selective PI3K inhibitor) and treated with IGF-1 (100 ng/ml) for 20 min.)

GSKalpha, Polyclonal Antibody (Cat# AAA515970)

Full Name
Anti-Phospho-GSKalpha (Ser21)
Reactivity
Human
Applications
EIA, IF, WB
Purity
Immunoaffinity chromatography
Pricing
$425/0.1 mg | $1,690/5x0.1 mg

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