Mouse anti-Human TDP2 Monoclonal Antibody | anti-TDP2 antibody

TDP2 (Tyrosyl-DNA Phosphodiesterase 2, Tyr-DNA Phosphodiesterase 2, hTDP2, 5'-tyrosyl-DNA Phosphodiesterase, 5'-Tyr-DNA Phosphodiesterase, AD022, AD-022, ETS1-associated Protein 2, EAP2, ETS1-associated Protein II, EAPII, TRAF and TNF Receptor-associated

Cat. Num. AAA6144978

• Gene Names: TDP2; EAP2; AD022; EAPII; TTRAP; hTDP2; dJ30M3.3
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TDP2; Monoclonal Antibody; TDP2 (Tyrosyl-DNA Phosphodiesterase 2; Tyr-DNA Phosphodiesterase 2; hTDP2; 5'-tyrosyl-DNA Phosphodiesterase; 5'-Tyr-DNA Phosphodiesterase; AD022; AD-022; ETS1-associated Protein 2; EAP2; ETS1-associated Protein II; EAPII; TRAF and TNF Receptor-associated; EC=3.1.4.-; dJ30M3.3; RP1-30M3.3; anti-TDP2 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2b,k
• Clone Number: 3D11
• Specificity: Recognizes human TTRAP.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-TDP2 antibody: ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
• Application Notes: IHC-P: 1.5ug/ml; Applications are based on unconjugated antibody.
• Immunogen: Full length recombinant corresponding to aa1-363 from human TTRAP (AAH17553) with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: MELGSCLEGGREAAEEEGEPEVKKRRLLCVEFASVASCDAAVAQCFLAENDWEMERALNSYFEPPVEESALERRPETISEPKTYVDLTNEETTDSTTSKISPSEDTQQENGSMFSLITWNIDGLDLNNLSERARGVCSYLALYSPDVIFLQEVIPPYYSYLKKRSSNYEIITGHEEGYFTAIMLKKSRVKLKSQEIIPFPSTKMMRNLLCVHVNVSGNELCLMTSHLESTRGHAAERMNQLKMVLKKMQEAPESATVIFAGDTNLRDREVTRCGGLPNNIVDVWEFLGKPKHCQYTWDTQMNSNLGITAACKLRFDRIFFRAAAEEGHIIPRSLDLLGLEKLDCGRFPSDHWGLLCNLDIIL
• Conjugate: Biotin
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (65.93kD).)

Immunohistochemistry (IHC)

(Immunoperoxidase of monoclonal antibody to TTRAP on formalin-fixed paraffin-embedded human testis. [antibody concentration 1.5ug/ml].)

Testing Data

(Detection limit for recombinant GST tagged TTRAP is 0.3ng/ml as a capture antibody.)

Product Categories/Family for anti-TDP2 antibody

Antibodies; Enzymes

NCBI and Uniprot Product Information

• NCBI GI #: 34782842
• NCBI GeneID: 51567
• Molecular Weight: 41KD
• NCBI Official Full Name: Homo sapiens TRAF and TNF receptor associated protein, mRNA
• NCBI Official Synonym Full Names: tyrosyl-DNA phosphodiesterase 2
• NCBI Official Symbol: TDP2
• NCBI Official Synonym Symbols: EAP2; AD022; EAPII; TTRAP; hTDP2; dJ30M3.3
• NCBI Protein Information: tyrosyl-DNA phosphodiesterase 2
• Protein Family: Tyrosyl-DNA phosphodiesterase

NCBI Description

This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008]