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C1orf187 Positive Control | DRAXIN positive control

C1orf187 Positive Control

Gene Names
DRAXIN; UNQ3119; neucrin; AGPA3119; C1orf187
Applications
Western Blot
Synonyms
C1orf187; C1orf187 Positive Control; AGPA3119; Chromosome 1 open reading frame 187; Dorsal inhibitory axon guidance protein; Dorsal repulsive axon guidance protein; DRAXIN; FLJ34999; MGC117222; Neucrin; OTTHUMP00000002262; UNQ3119 antibody; DRAXIN positive control
Ordering
For Research Use Only!
Form/Format
Western Blot Positive Control
Sequence Length
349
Applicable Applications for DRAXIN positive control
Western Blot (WB)
Application Notes
Western Blot: 1:500-1:1,000
Molecular Function
Wnt signaling pathway
Structure
Interacts with LRP6
Subcellular Location
Secreted
Preparation and Storage
-20 degree C for long term storage
Related Product Information for DRAXIN positive control
Western Blot Positive Control Draxin
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,650 Da
NCBI Official Full Name
draxin
NCBI Official Synonym Full Names
dorsal inhibitory axon guidance protein
NCBI Official Symbol
DRAXIN
NCBI Official Synonym Symbols
UNQ3119; neucrin; AGPA3119; C1orf187
NCBI Protein Information
draxin
UniProt Protein Name
Draxin
Protein Family
UniProt Gene Name
DRAXIN
UniProt Entry Name
DRAXI_HUMAN

Uniprot Description

DRAXIN: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta- catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. Belongs to the draxin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1p36.22

Cellular Component: extracellular region

Molecular Function: protein binding

Biological Process: axon guidance; commissural neuron differentiation in the spinal cord; dorsal spinal cord development; forebrain development; negative regulation of axon extension; negative regulation of neuron apoptosis; Wnt receptor signaling pathway

Research Articles on DRAXIN

Similar Products

Product Notes

The DRAXIN draxin (Catalog #AAA542711) is a Positive Control and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's C1orf187 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:500-1:1,000. Researchers should empirically determine the suitability of the DRAXIN draxin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C1orf187, Positive Control" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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