Western Blot (WB)
(TRPV1 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TRPV1 antibody detected the TRPV1 protein (arrow).)
Rabbit anti-Human TRPV1 Polyclonal Antibody | anti-TRPV1 antibody
TRPV1 Antibody (N-term)
Western Blot (WB)
(TRPV1 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TRPV1 antibody detected the TRPV1 protein (arrow).)
Western Blot (WB)
(TRPV1 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TRPV1 antibody detected the TRPV1 protein (arrow).)
Immunohistochemistry (IHC)
(TRPV1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRPV1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(TRPV1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRPV1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
peppers, elicits a sensation of burning pain by selectively
activating sensory neurons that convey information about noxious
stimuli to the central nervous system. The protein encoded by this
gene is a receptor for capsaicin and is a non-selective cation
channel that is structurally related to members of the TRP family
of ion channels. This receptor is also activated by increases in
temperature in the noxious range, suggesting that it functions as a
transducer of painful thermal stimuli in vivo. Four transcript
variants encoding the same protein, but with different 5' UTR
sequence, have been described for this gene.
Cantero-Recasens, G., et al. J. Biol. Chem. 285(36):27532-27535(2010)
Shieh, K.R., et al. Neurogastroenterol. Motil. 22(9):971-977(2010)
Cheng, L.E., et al. Neuron 67(3):373-380(2010)
Westlund, K.N., et al. Mol Pain 6, 46 (2010) :
NCBI and Uniprot Product Information
NCBI Description
Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
TRPV1: a receptor for capsaicin and a non-selective cation channel that is structurally related to members of the TRP family of ion channels. Activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo.
Protein type: Membrane protein, multi-pass; Channel, cation; Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 17p13.2
Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; integral to membrane; cell junction; intrinsic to plasma membrane
Molecular Function: calmodulin binding; transmembrane receptor activity; excitatory extracellular ligand-gated ion channel activity; calcium-release channel activity; calcium channel activity; phosphoprotein binding; ATP binding
Biological Process: cell surface receptor linked signal transduction; transport; chemosensory behavior; thermoception; transmembrane transport
Research Articles on TRPV1
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Product Notes
The TRPV1 trpv1 (Catalog #AAA9205287) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 124-153. The TRPV1 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRPV1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the TRPV1 trpv1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRPV1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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