Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using TRPV1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 60s.)
Rabbit TRPV1 Polyclonal Antibody | anti-TRPV1 antibody
TRPV1 Polyclonal Antibody
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using TRPV1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 60s.)
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using TRPV1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 60s.)
NCBI and Uniprot Product Information
Molecular Weight: 839
NCBI Description
Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
TRPV1: a receptor for capsaicin and a non-selective cation channel that is structurally related to members of the TRP family of ion channels. Activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo.
Protein type: Membrane protein, integral; Receptor, misc.; Channel, cation; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 17p13.2
Cellular Component: cell junction; cell soma; cytosol; dendrite; external side of plasma membrane; integral to membrane; integral to plasma membrane; intrinsic to plasma membrane; plasma membrane; postsynaptic membrane
Molecular Function: ATP binding; calcium channel activity; calcium-release channel activity; calmodulin binding; chloride channel regulator activity; excitatory extracellular ligand-gated ion channel activity; identical protein binding; phosphoprotein binding; transmembrane receptor activity
Biological Process: behavioral response to pain; cell surface receptor linked signal transduction; chemosensory behavior; detection of chemical stimulus involved in sensory perception of pain; detection of temperature stimulus involved in sensory perception of pain; diet induced thermogenesis; elevation of cytosolic calcium ion concentration; fever; glutamate secretion; lipid metabolic process; microglial cell activation; peptide secretion; positive regulation of apoptosis; positive regulation of nitric oxide biosynthetic process; response to heat; response to peptide hormone stimulus; response to pH; sensory perception of mechanical stimulus; smooth muscle contraction involved in micturition; thermoception; transmembrane transport; transport
Research Articles on TRPV1
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Product Notes
The TRPV1 trpv1 (Catalog #AAA9129440) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRPV1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TRPV1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500 - 1:2000. Researchers should empirically determine the suitability of the TRPV1 trpv1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRPV1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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