Rabbit STK10-a Polyclonal Antibody | anti-phospho-STK10-a antibody
Anti-phospho-STK10-a (Ser482 Ser486 Ser490)
Reactivity
Human, Mouse, Rat, Zebrafish
Applications
Western Blot
Purity
Affinity Chromatography
Synonyms
STK10-a; Polyclonal Antibody; Anti-phospho-STK10-a (Ser482 Ser486 Ser490); anti-phospho-STK10-a antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat, Zebrafish
Clonality
Polyclonal
Isotype
Rabbit, IgG
Specificity
Recognizes the STK10-a protein phosphorylated at serine 482/486/490
Purity/Purification
Affinity Chromatography
Form/Format
100 ul in 10mM HEPES (pH7.5), 150mMNaCl, 100 ug per ml BSA and 50% glycerol.
Applicable Applications for anti-phospho-STK10-a antibody
Western Blot (WB)
Application Notes
WB: 1:1,000
Immunogen
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser482/486/490 conjugated to KLH
Preparation and Storage
Store at 4 degree C (add 0.1% NaN3) for several months, and at -20 degree C for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Related Product Information for anti-phospho-STK10-a antibody
Polo-like kinase (PLK) plays an important role in cell cycle regulation. PLK is also required for bipolar spindle formation, activation of the anaphase-promoting complex/cyclosome, and cytokinesis. Deregulation of PLKs often results in abnormalities in centrosome duplication, maturation and/or microtubule dynamics (1). STK10-a, which is also known as PLKK is likely responsible for activating PLK. STK10-a itself is activated by phosphorylation at Ser482, Ser486 and Ser490 (2).
Product Categories/Family for anti-phospho-STK10-a antibody
References
1. Nigg, EA. et al: Dynamic changes in nuclear architecture during mitosis: on the role of protein phosphorylation in spindle assembly and chromosome segregation. Exp Cell Res. 1996 Dec 15;229
2. Erikson E et al. A feedback loop in the polo-like kinase activation pathway. J Biol Chem. 2004, 279:32219-32224.
2. Erikson E et al. A feedback loop in the polo-like kinase activation pathway. J Biol Chem. 2004, 279:32219-32224.
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Product Notes
The phospho-STK10-a (Catalog #AAA516220) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-phospho-STK10-a (Ser482 Ser486 Ser490) reacts with Human, Mouse, Rat, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's STK10-a can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1,000. Researchers should empirically determine the suitability of the phospho-STK10-a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STK10-a, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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