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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/20.)

Rabbit anti-Human, Mouse SEMA6A Polyclonal Antibody | anti-SEMA6A antibody

SEMA6A Antibody

Gene Names
SEMA6A; VIA; SEMA; HT018; SEMAQ; SEMA6A1
Reactivity
Human, Mouse
Applications
Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
SEMA6A; Polyclonal Antibody; SEMA6A Antibody; VIA; SEMA; HT018; SEMAQ; SEMA6A1; anti-SEMA6A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total SEMA6A protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
1.2 mg/ml (varies by lot)
Sequence Length
1047
Applicable Applications for anti-SEMA6A antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:25-1:100
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to a region derived from internal residues of human sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Target Name
SEMA6A
Preparation and Storage
Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/20.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/20.)
Related Product Information for anti-SEMA6A antibody
The transmembrane semaphorin SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection. Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system.
Product Categories/Family for anti-SEMA6A antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
116,336 Da
NCBI Official Full Name
semaphorin-6A isoform 1
NCBI Official Synonym Full Names
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
NCBI Official Symbol
SEMA6A
NCBI Official Synonym Symbols
VIA; SEMA; HT018; SEMAQ; SEMA6A1
NCBI Protein Information
semaphorin-6A
UniProt Protein Name
Semaphorin-6A
Protein Family
UniProt Gene Name
SEMA6A
UniProt Synonym Gene Names
KIAA1368; SEMAQ; Sema VIA; SEMA6A-1
UniProt Entry Name
SEM6A_HUMAN

NCBI Description

The transmembrane semaphorin SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection (Leighton et al., 2001 [PubMed 11242070]).[supplied by OMIM, Feb 2011]

Uniprot Description

SEMA6A: a single-pass type I membrane protein of the semaphorin family that can act as repulsive axon guidance cues. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation. Active as a homodimer or oligomer. Interacts with EVL. Two isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 5q23.1

Cellular Component: axon; plasma membrane; integral to membrane

Molecular Function: protein binding; receptor activity

Biological Process: nervous system development; axon guidance; organ morphogenesis; cell surface receptor linked signal transduction; apoptosis; cytoskeleton organization and biogenesis

Research Articles on SEMA6A

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Product Notes

The SEMA6A sema6a (Catalog #AAA9401521) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SEMA6A Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SEMA6A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the SEMA6A sema6a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SEMA6A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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