Rabbit anti-Human NF-1A Polyclonal Antibody | anti-NF-1A antibody

NF-1A antibody (pAb)

Cat. Num. AAA388473

• Reactivity: Human
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
• Synonyms: NF-1A; Polyclonal Antibody; NF-1A antibody (pAb); NFIX; MRSHSS; SOTOS2; anti-NF-1A antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Form/Format: Rabbit serum containing 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

• Applicable Applications for anti-NF-1A antibody: Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
• Application Notes: Applications Validated:; ICC/IF: 1:250-1:500 dilution; WB: 1:1,000-1:5,000 dilution
• Immunogen: This NF-1A antibody was raised against a synthetic peptide corresponding to amino acid residue(s) 478-492 of human NF-1A.
• Preparation and Storage: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20 degree C for up to 2 years. Keep all reagents on ice when not in storage.1ug/ul

Immunofluorescence (IF)

(NF-1A antibody (pAb) tested by immunofluorescence. Detection of NF-1A antibody by immunofluorescence. Human Astrocytes-cerebellar (HA-c) cells were stained with NF-1A antibody at a 1:500 dilution. Green: NF-1A antibody (pAb) Red: Vimentin)

Related Product Information for anti-NF-1A antibody

Short Description: Our NF-1A antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunocytochemistry, Immunofluorescence, Immunohistochemistry and Western blot; it has been shown to react with Human samples.

Background: NF-1A (NF-1, Nuclear factor-1) is a ubiquitous 47 kDa dimeric DNA-binding protein whose recognition sequence, TGG(C/A)N(5)GCCAA, is found in the genomes of a number of DNA viruses. The same sequence occurs frequently in the human genome. The NF-1 protein stimulates initiation of adenovirus DNA replication in vitro and is capable of stimulating the transcription of genes in cooperation with other factors, such as the estrogen receptor. The Nuclear factor-1 (NF-1) family of transcription factors are encoded by the genes NF-1A, NF-1B2, NF-1C and NF-1X, and feature a highly conserved N-terminal DNA binding region and a variable C-terminal transcriptional activation or repression domain. NF-1 binding controls the expression of many target genes, including insulin, TGF-b, nucleotide, steroid hormone and vitamin synthetic genes, TNFa and FSH. NF-1 transcripts can be differentially spliced and the resultant protein variants homo- and heterodimerize, allowing for multiple potential transcriptional activation and repression activities.

Product Categories/Family for anti-NF-1A antibody

Primary Antibodies

NCBI and Uniprot Product Information

• Molecular Weight: 60kDa