Testing Data
Rabbit anti-Human JHDM1D Polyclonal Antibody | anti-JHDM1D antibody
JHDM1D Antibody
Gene Names
KDM7A; JHDM1D
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Synonyms
JHDM1D; Polyclonal Antibody; JHDM1D Antibody; anti-JHDM1D antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Form/Format
Purified by peptide affinity column containing 0.5% BSA and 0.02% NaN3
Sequence Length
941
Applicable Applications for anti-JHDM1D antibody
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Peptide ELISA: 1:160,000
WB: 1:1,000-2,000
IHC: 1:100-1:500
WB: 1:1,000-2,000
IHC: 1:100-1:500
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Testing Data
Testing Data
Testing Data
Testing Data
Related Product Information for anti-JHDM1D antibody
Rabbit polyclonal JHDM1D (1) antibody was raised against a peptide from 586-601 of human JHDM1D.
Product Categories/Family for anti-JHDM1D antibody
References
(1) Huang, C., Xiang, Y., Wang, Y.et al. Dual-specificity histone demethylase KIAA1718 (KDM7A) regulates neural differentiation through FGF4. Cell Res. 20 (2), 154-165 (2010).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
92,001 Da
NCBI Official Full Name
lysine-specific demethylase 7A
NCBI Official Synonym Full Names
lysine demethylase 7A
NCBI Official Symbol
KDM7A
NCBI Official Synonym Symbols
JHDM1D
NCBI Protein Information
lysine-specific demethylase 7A
UniProt Protein Name
Lysine-specific demethylase 7A
UniProt Gene Name
KDM7A
UniProt Synonym Gene Names
JHDM1D; KDM7; KIAA1718
Uniprot Description
Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate.
Research Articles on JHDM1D
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Product Notes
The JHDM1D kdm7a (Catalog #AAA859314) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The JHDM1D Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's JHDM1D can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Peptide ELISA: 1:160,000 WB: 1:1,000-2,000 IHC: 1:100-1:500. Researchers should empirically determine the suitability of the JHDM1D kdm7a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "JHDM1D, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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