Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 47806(KDM7A Antibody) at dilution 1/35.(Original magnification: 200))
Rabbit anti-Human, Mouse KDM7A Polyclonal Antibody | anti-KDM7A antibody
KDM7A Antibody
Gene Names
KDM7A; JHDM1D
Reactivity
Human, Mouse
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
KDM7A; Polyclonal Antibody; KDM7A Antibody; JHDM1D; anti-KDM7A antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total KDM7A protein.
Purity/Purification
Antigen affinity purification
Form/Format
pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
1 mg/mL (varies by lot)
Sequence Length
941
Applicable Applications for anti-KDM7A antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:30-150
Immunogen
Synthetic peptide of human KDM7A
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 47806(KDM7A Antibody) at dilution 1/35.(Original magnification: 200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 47806(KDM7A Antibody) at dilution 1/35.(Original magnification: 200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 47806(KDM7A Antibody) at dilution 1/35.(Original magnification: 200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 47806(KDM7A Antibody) at dilution 1/35.(Original magnification: 200))
Related Product Information for anti-KDM7A antibody
Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate.
Product Categories/Family for anti-KDM7A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
92,001 Da
NCBI Official Full Name
lysine-specific demethylase 7A
NCBI Official Synonym Full Names
lysine demethylase 7A
NCBI Official Symbol
KDM7A
NCBI Official Synonym Symbols
JHDM1D
NCBI Protein Information
lysine-specific demethylase 7A
UniProt Protein Name
Lysine-specific demethylase 7A
Protein Family
UniProt Gene Name
KDM7A
UniProt Synonym Gene Names
JHDM1D; KDM7; KIAA1718
Uniprot Description
Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate.
Research Articles on KDM7A
Similar Products
Product Notes
The KDM7A kdm7a (Catalog #AAA9430787) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KDM7A Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KDM7A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:30-150. Researchers should empirically determine the suitability of the KDM7A kdm7a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KDM7A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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