Western Blot (WB)
(Mouse Gsk3b Antibody (N-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Gsk3b antibody detected the Gsk3b protein (arrow).)
Rabbit Gsk3b Polyclonal Antibody | anti-Gsk3b antibody
Mouse Gsk3b Antibody (N-term)
Western Blot (WB)
(Mouse Gsk3b Antibody (N-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Gsk3b antibody detected the Gsk3b protein (arrow).)
Western Blot (WB)
(Mouse Gsk3b Antibody (N-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Gsk3b antibody detected the Gsk3b protein (arrow).)
Immunohistochemistry (IHC)
(Mouse Gsk3b Antibody (N-term) (MBS9213022)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Gsk3b Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Mouse Gsk3b Antibody (N-term) (MBS9213022)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Gsk3b Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Graham, J.A., et al. J. Biol. Chem. 285(43):32852-32859(2010)
Ahmad, I., et al. Oncogene (2010) In press :
Asada, N., et al. J. Neurosci. 30(26):8852-8865(2010)
Carew, R.M., et al. BMC Dev. Biol. 10, 73 (2010) :
NCBI and Uniprot Product Information
Uniprot Description
GSK3B: a proline-directed protein kinase of the GSK family. Phosphorylates and inactivates glycogen synthase. Participates in the Wnt signaling pathway. Involved in energy metabolism, neuronal cell development, and body pattern formation
Protein type: EC 2.7.11.26; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Protein kinase, CMGC; CMGC group; GSK family; GSK subfamily
Cellular Component: centrosome; protein complex; dendritic spine; ribonucleoprotein complex; beta-catenin destruction complex; cytosol; lipid raft; nucleoplasm; growth cone; cell soma; membrane; perinuclear region of cytoplasm; cytoplasm; plasma membrane; dendritic shaft; nucleus
Molecular Function: p53 binding; beta-catenin binding; nucleotide binding; transcription factor binding; protein kinase binding; protein kinase activity; transferase activity; integrin binding; NF-kappaB binding; ionotropic glutamate receptor binding; protein serine/threonine kinase activity; protein binding; ubiquitin protein ligase binding; transferase activity, transferring phosphorus-containing groups; tau-protein kinase activity; kinase activity; tau protein binding; ATP binding
Biological Process: circadian rhythm; fat cell differentiation; glycogen metabolic process; negative regulation of MAP kinase activity; genetic imprinting; re-entry into mitotic cell cycle; positive regulation of protein binding; positive regulation of apoptosis; multicellular organismal development; protein amino acid autophosphorylation; positive regulation of axon extension; establishment and/or maintenance of cell polarity; rhythmic process; Wnt receptor signaling pathway through beta-catenin; protein amino acid phosphorylation; positive regulation of protein export from nucleus; protein export from nucleus; negative regulation of protein binding; positive regulation of cell-matrix adhesion; cell differentiation; myoblast fusion; ER overload response; nervous system development; regulation of microtubule-based process; cell migration; Wnt receptor signaling pathway; hippocampus development; myotube differentiation; negative regulation of dendrite morphogenesis; cytoskeleton organization and biogenesis; negative regulation of NFAT protein import into nucleus; positive regulation of peptidyl-serine phosphorylation; negative regulation of signal transduction; cell proliferation; negative regulation of neuron maturation; organ morphogenesis; peptidyl-serine phosphorylation; positive regulation of protein complex assembly; axonogenesis; establishment of cell polarity; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; carbohydrate metabolic process; epithelial to mesenchymal transition; positive regulation of transcription from RNA polymerase II promoter; phosphorylation; negative regulation of protein complex assembly; regulation of neuronal synaptic plasticity; negative regulation of apoptosis
Research Articles on Gsk3b
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Product Notes
The Gsk3b gsk3b (Catalog #AAA9213022) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 30-59. The Mouse Gsk3b Antibody (N-term) reacts with Mouse (Predicted Reactivity: Human, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's Gsk3b can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the Gsk3b gsk3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Gsk3b, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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