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Western Blot (WB) (Western blot analysis of GNRH2 Antibody (Center) in MDA-MB435 cell line lysates (35ug/lane). GNRH2 (arrow) was detected using the purified Pab.)

Rabbit anti-Human GNRH2 Polyclonal Antibody | anti-GNRH2 antibody

GNRH2 Antibody (Center)

Gene Names
GNRH2; GnRH-II; LH-RHII
Reactivity
Human
Applications
Western Blot, ELISA, Flow Cytometry, Functional Assay
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
GNRH2; Polyclonal Antibody; GNRH2 Antibody (Center); Progonadoliberin-2; Progonadoliberin II; Gonadoliberin-2; Gonadoliberin II; Gonadotropin-releasing hormone II; GnRH II; Luliberin II; Luteinizing hormone-releasing hormone II; LH-RH II; GnRH-associated peptide 2; GnRH-associated peptide II; anti-GNRH2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This GNRH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-53 amino acids from the Central region of human GNRH2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
26-53
Sequence Length
120
Applicable Applications for anti-GNRH2 antibody
Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of GNRH2 Antibody (Center) in MDA-MB435 cell line lysates (35ug/lane). GNRH2 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of GNRH2 Antibody (Center) in MDA-MB435 cell line lysates (35ug/lane). GNRH2 (arrow) was detected using the purified Pab.)

Flow Cytometry (FC/FACS)

(GNRH2 Antibody (Center) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (GNRH2 Antibody (Center) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Related Product Information for anti-GNRH2 antibody
The protein encoded by this gene is a preproprotein that is cleaved to form a secreted 10 aa peptide hormone. The secreted decapeptide regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones.
Product Categories/Family for anti-GNRH2 antibody
References
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Poon, S.L., et al. Mol. Endocrinol. 23(10):1646-1656(2009)
Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009)
Palmieri, R.T., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3567-3572(2008)
Poon, S.L., et al. Endocrinology 149(10):5162-5171(2008)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
12918
NCBI Official Full Name
progonadoliberin-2 isoform a preproprotein
NCBI Official Synonym Full Names
gonadotropin-releasing hormone 2
NCBI Official Symbol
GNRH2
NCBI Official Synonym Symbols
GnRH-II; LH-RHII
NCBI Protein Information
progonadoliberin-2
UniProt Protein Name
Progonadoliberin-2
Protein Family
UniProt Gene Name
GNRH2
UniProt Synonym Gene Names
GnRH II; LH-RH II
UniProt Entry Name
GON2_HUMAN

NCBI Description

The protein encoded by this gene is a preproprotein that is cleaved to form a secreted 10 aa peptide hormone. The secreted decapeptide regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones. Three transcript variants that encode unique proproteins but the same peptide hormone have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

GNRH2: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones. Belongs to the GnRH family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: extracellular region

Molecular Function: hormone activity

Biological Process: multicellular organismal development; signal transduction

Research Articles on GNRH2

Similar Products

Product Notes

The GNRH2 gnrh2 (Catalog #AAA9201553) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 26-53. The GNRH2 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GNRH2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the GNRH2 gnrh2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GNRH2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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