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GNRH2 recombinant protein
GNRH2 Protein, Human, Recombinant (hFc Tag)
Gene Names
GNRH2; GnRH-II; LH-RHII
Purity
>95% as determined by SDS-PAGE
Synonyms
GNRH2; GNRH2 Protein; Human; Recombinant (hFc Tag); Human GNRH2/GnRH II Protein (Fc Tag); GnRH-II Protein; LH-RHII Protein; gonadotropin releasing hormone 2; GNRH2 recombinant protein
Host
HEK293 Cells
Purity/Purification
>95% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Gln24-Val120
Species
Human
Endotoxin
<1.0EU per ug protein as determined by the LAL method.
Predicted N Terminal
Glu
Tag
N-human IgG1-Fc
Protein Construction
A DNA sequence encoding the human GNRH2 (NP_001492.1)(Gln24-Val120) was expressed with the Fc region of human IgG1 at the N-terminus.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
SDS-Page
SDS-Page
Related Product Information for GNRH2 recombinant protein
Background: GNRH2 (Gonadotropin-Releasing Hormone 2) is a Protein Coding gene. This gene is a member of the gonadotropin-releasing hormone (GnRH) gene family. Proteins encoded by members of this gene family are proteolytically cleaved to form neuropeptides which, in part, regulate reproductive functions by stimulating the production and release of the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH). 3 alternatively spliced human isoforms have been reported. The second mammalian isoform (GNRH2) is an ineffective stimulant of gonadotropin release. Given that pigs lack testicular GNRHR1, these data may indicate that GNRH2 and its receptor are involved in the autocrine or paracrine regulation of testosterone secretion. Diseases associated with GNRH2 include Colon Mucinous Adenocarcinoma and Ovarian Cancer.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
12,918 Da
NCBI Official Full Name
progonadoliberin-2 isoform a preproprotein
NCBI Official Synonym Full Names
gonadotropin-releasing hormone 2
NCBI Official Symbol
GNRH2
NCBI Official Synonym Symbols
GnRH-II; LH-RHII
NCBI Protein Information
progonadoliberin-2; luliberin II; progonadoliberin II; luteinizing hormone-releasing hormone II
UniProt Protein Name
Progonadoliberin-2
Protein Family
UniProt Gene Name
GNRH2
UniProt Synonym Gene Names
GnRH II; LH-RH II
UniProt Entry Name
GON2_HUMAN
NCBI Description
The protein encoded by this gene is a preproprotein that is cleaved to form a secreted 10 aa peptide hormone. The secreted decapeptide regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones. Three transcript variants that encode unique proproteins but the same peptide hormone have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.
Research Articles on GNRH2
Similar Products
Product Notes
The GNRH2 gnrh2 (Catalog #AAA8121872) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Gln24-Val1 20. It is sometimes possible for the material contained within the vial of "GNRH2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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