Western Blot (WB)
(Western blot analysis of FRMPD1 in K562 cell lysate with FRMPD1 antibody at (A) 1 and (B) 2 ug/mL.)
Rabbit anti-Human FRMPD1 Polyclonal Antibody | anti-FRMPD1 antibody
FRMPD1 Antibody
Gene Names
FRMPD1; FRMD2
Reactivity
Human
Applications
ELISA, Western Blot, Immunofluorescence
Purity
Affinity chromatography purified via peptide column
Synonyms
FRMPD1; Polyclonal Antibody; FRMPD1 Antibody; FERM and PDZ domain-containing 1; FRMD2; anti-FRMPD1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
1578
Applicable Applications for anti-FRMPD1 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Immunogen Type
Peptide
Immunogen Description
Raised against a 15 amino acid peptide from near the carboxy terminus of human FRMPD1.
Target Name
FRMPD1
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of FRMPD1 in K562 cell lysate with FRMPD1 antibody at (A) 1 and (B) 2 ug/mL.)
Western Blot (WB)
(Western blot analysis of FRMPD1 in K562 cell lysate with FRMPD1 antibody at (A) 1 and (B) 2 ug/mL.)
Immunofluorescence (IF)
(Immunofluorescence of FRMPD1 in K562 cells with FRMPD1 antibody at 20 ug/mL.)
Immunofluorescence (IF)
(Immunofluorescence of FRMPD1 in K562 cells with FRMPD1 antibody at 20 ug/mL.)
Related Product Information for anti-FRMPD1 antibody
The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain. FRMPD1 was initially identified through a yeast two-hybrid screening with Activator of G-protein signaling 3 (AGS3), a protein that acts to stabilize the GDP-bound conformation of Gai, as the bait. FRMPD1 binds to the tetratricopeptide repeat of AGS3 and stabilizes AGS3 in a membrane environment. Suppression of FRMPD1 in Cath.a-differentiated neuronal cells decreased the level of endogenous AGS3 in membrane fractions by ~50% and enhanced the inhibition of forskolin-induced increases in cAMP. Co-immunoprecipitation studies indicate that the interaction of AGS3 with FRMPD1 is mutually exclusive with the interaction of AGS3 with Gai3, suggesting that FRMPD1 may position AGS3 in the membrane where it can then interact with Galphai.
Product Categories/Family for anti-FRMPD1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
75,420 Da
NCBI Official Full Name
FERM and PDZ domain-containing protein 1
NCBI Official Synonym Full Names
FERM and PDZ domain containing 1
NCBI Official Symbol
FRMPD1
NCBI Official Synonym Symbols
FRMD2
NCBI Protein Information
FERM and PDZ domain-containing protein 1
UniProt Protein Name
FERM and PDZ domain-containing protein 1
Protein Family
UniProt Gene Name
FRMPD1
UniProt Synonym Gene Names
FRMD2; KIAA0967
UniProt Entry Name
FRPD1_HUMAN
Uniprot Description
FRMPD1: Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1.
Chromosomal Location of Human Ortholog: 9p13.2
Cellular Component: cytoskeleton; plasma membrane; cytosol
Research Articles on FRMPD1
1. LGN-TPR motifs are versatile and capable of recognizing multiple targets via diverse binding modes.
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Product Notes
The FRMPD1 frmpd1 (Catalog #AAA9413056) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FRMPD1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FRMPD1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF). Researchers should empirically determine the suitability of the FRMPD1 frmpd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FRMPD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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