Western Blot (WB)
(Western blot analysis of FRMPD4 in SK-N-SH cell lysate with FRMPD4 antibody at (A) 1 and (B) 2 ug/mL.)
Rabbit anti-Human FRMPD4 Polyclonal Antibody | anti-FRMPD4 antibody
FRMPD4 Antibody
Gene Names
KIAA0195; TMEM94
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
FRMPD4; Polyclonal Antibody; FRMPD4 Antibody; FERM and PDZ domain-containing 4; Preso; PDZD10; PDZK10; anti-FRMPD4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
1356
Applicable Applications for anti-FRMPD4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen Type
Peptide
Immunogen Description
Raised against an 18 amino acid peptide from near the center of human FRMPD4.
Target Name
FRMPD4
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of FRMPD4 in SK-N-SH cell lysate with FRMPD4 antibody at (A) 1 and (B) 2 ug/mL.)
Western Blot (WB)
(Western blot analysis of FRMPD4 in SK-N-SH cell lysate with FRMPD4 antibody at (A) 1 and (B) 2 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of FRMPD4 in human brain tissue with FRMPD4 antibody at 5 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of FRMPD4 in human brain tissue with FRMPD4 antibody at 5 ug/mL.)
Related Product Information for anti-FRMPD4 antibody
The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain. FRMPD4, also known as Preso, also contains another protein interaction domain termed WW (domain with two conserved Trp residues) at its amino terminus. It was identified through a yeast two-hybrid screen using the PDZ domain of PSD-95 as bait and is highly expressed in multiple regions of the brain and is enriched in the postsynaptic density (PSD) fractions. Overexpression of FRMPD4 in cultured hippocampal neurons significantly increased the linear density of dendritic spines without changing their length and width; conversely, knockdown experiments using RNAi caused a decrease in spine density, indicating FRMPD4 positively regulates dendritic spine density but not morphology. The decreased level of FRMPD4 also resulted in reduced levels of excitatory synaptic transmission, suggesting that FRMPD4 is required for maintenance of excitatory synaptic transmission.
Product Categories/Family for anti-FRMPD4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
154,257 Da
NCBI Official Full Name
uncharacterized protein KIAA0195
NCBI Official Synonym Full Names
KIAA0195
NCBI Official Symbol
KIAA0195
NCBI Official Synonym Symbols
TMEM94
NCBI Protein Information
uncharacterized protein KIAA0195
UniProt Protein Name
Uncharacterized protein KIAA0195
Protein Family
UniProt Gene Name
KIAA0195
UniProt Synonym Gene Names
TMEM94
UniProt Entry Name
K0195_HUMAN
Uniprot Description
KIAA0195: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 17q25.1
Cellular Component: nucleoplasm; integral to membrane
Research Articles on FRMPD4
Similar Products
Product Notes
The FRMPD4 kiaa0195 (Catalog #AAA9406280) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FRMPD4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FRMPD4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the FRMPD4 kiaa0195 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FRMPD4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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