Rabbit SCAMP4 Polyclonal Antibody | anti-SCAMP4 antibody

SCAMP4 Antibody

Cat. Num. AAA9413342

• Gene Names: SCAMP4; SCAMP-4
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity chromatography purified via peptide column
• Synonyms: SCAMP4; Polyclonal Antibody; SCAMP4 Antibody; Secretory carrier membrane protein 4; anti-SCAMP4 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Purity/Purification: Affinity chromatography purified via peptide column
• Form/Format: Supplied in PBS containing 0.02% sodium azide.
• Sequence Length: 229

• Applicable Applications for anti-SCAMP4 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen Type: Peptide
• Immunogen Description: Raised against a 15 amino acid peptide near the carboxy terminus of human SCAMP4.
• Target Name: SCAMP4
• Preparation and Storage: Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of SCAMP4 in 3T3 cell lysate with SCAMP4 antibody at (A) 1 and (B) 2 ug/mL.)

Immunohistochemistry (IHC)

(Immunohistochemistry of SCAMP4 in human brain tissue with SCAMP4 antibody at 2.5 ug/mL.)

Related Product Information for anti-SCAMP4 antibody

Secretory carrier membrane proteins (SCAMPs) are integral membrane proteins seen in secretory and endocytic carriers that are thought to play roles in membrane trafficking. One member of this family, SCAMP4, lacks the putative calcium binding and leucine zipper structures as well as the protein-protein interacting NPF domains common to most SCAMP family members. In rats, SCAMP4 mRNA is repressed by progesterone in brain regions associated with female sexual behavior. At least three isoforms of SCAMP4 are known to exist. This SCAMP4 antibody is predicted to not cross-react with any other member of the secretory carrier membrane protein family.

Product Categories/Family for anti-SCAMP4 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 17738287
• NCBI GeneID: 113178
• NCBI Accession #: NP_524558
• NCBI GenBank Nucleotide #: NM_079834.2
• Molecular Weight: 15,097 Da
• NCBI Official Full Name: secretory carrier-associated membrane protein 4
• NCBI Official Synonym Full Names: secretory carrier membrane protein 4
• NCBI Official Symbol: SCAMP4
• NCBI Official Synonym Symbols: SCAMP-4
• NCBI Protein Information: secretory carrier-associated membrane protein 4
• UniProt Protein Name: Secretory carrier-associated membrane protein 4
• Protein Family: Secretory carrier-associated membrane protein
• UniProt Gene Name: SCAMP4
• UniProt Synonym Gene Names: Secretory carrier membrane protein 4
• UniProt Entry Name: SCAM4_HUMAN

NCBI Description

Secretory carrier membrane proteins (SCAMPs) are widely distributed integral membrane proteins implicated in membrane trafficking. Most SCAMPs (e.g., SCAMP1; MIM 606911) have N-terminal cytoplasmic NPF (arg-pro-phe) repeats, 4 central transmembrane regions, and a short C-terminal cytoplasmic tail. These SCAMPs likely have a role in endocytosis that is mediated by their NPF repeats. Other SCAMPs, such as SCAMP4, lack the NPF repeats and are therefore unlikely to function in endocytosis (summary by Fernandez-Chacon and Sudhof, 2000 [PubMed 11050114]).[supplied by OMIM, Feb 2011]

Uniprot Description

SCAMP4: Probably involved in membrane protein trafficking. Belongs to the SCAMP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Vesicle; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: integral to membrane

Biological Process: protein transport