Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using at dilution 1/35.)
Rabbit anti-Human, Mouse CERS6 Polyclonal Antibody | anti-CERS6 antibody
CERS6 Antibody
Gene Names
CERS6; CERS5; LASS6
Reactivity
Human, Mouse
Applications
Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
CERS6; Polyclonal Antibody; CERS6 Antibody; CERS5; LASS6; anti-CERS6 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total CERS6 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
2.4 mg/ml (varies by lot)
Sequence Length
392
Applicable Applications for anti-CERS6 antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:50-1:200
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to a region derived from internal residues of human ceramide synthase 6
Target Name
CERS6
Preparation and Storage
Store at -20 degree C
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using at dilution 1/35.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using at dilution 1/35.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human brain tissue using at dilution 1/35.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human brain tissue using at dilution 1/35.)
Related Product Information for anti-CERS6 antibody
The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they all are involved in sphingolipid synthesis. LASS6 is a widely expressed 384 amino acid endoplasmic reticulum, multi-pass membrane protein. On the luminal side of the endoplasmic reticulum membrane, the N-terminal asparagine residue is glycosylated. In cells deficient for CLN9, LASS6 corrects growth and apoptosis, and increases the levels of short ceramide species, such as C14:0- and C16:0-ceramides.
Product Categories/Family for anti-CERS6 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45,794 Da
NCBI Official Full Name
ceramide synthase 6 isoform 1
NCBI Official Synonym Full Names
ceramide synthase 6
NCBI Official Symbol
CERS6
NCBI Official Synonym Symbols
CERS5; LASS6
NCBI Protein Information
ceramide synthase 6
UniProt Protein Name
Ceramide synthase 6
Protein Family
UniProt Gene Name
CERS6
UniProt Synonym Gene Names
LASS6; CerS6
UniProt Entry Name
CERS6_HUMAN
Uniprot Description
LASS6: May be involved in sphingolipid synthesis or its regulation.
Protein type: Membrane protein, multi-pass; DNA-binding; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2q24.3
Cellular Component: endoplasmic reticulum membrane; nuclear membrane; membrane; endoplasmic reticulum; integral to membrane
Molecular Function: DNA binding; sphingosine N-acyltransferase activity
Biological Process: sphingolipid metabolic process; sphingolipid biosynthetic process; ceramide biosynthetic process
Research Articles on CERS6
Similar Products
Product Notes
The CERS6 cers6 (Catalog #AAA9414414) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CERS6 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CERS6 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:50-1:200. Researchers should empirically determine the suitability of the CERS6 cers6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CERS6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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