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Immunohistochemistry (IHC) (Anti-LASS6 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Rabbit CerS6 / LASS6 Polyclonal Antibody | anti-CERS6 antibody

Rabbit Polyclonal to Human CerS6 / LASS6

Gene Names
CERS6; CERS5; LASS6
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity Purified
Synonyms
CerS6 / LASS6; Polyclonal Antibody; Rabbit Polyclonal to Human CerS6 / LASS6; Anti-CerS6 / LASS6 Antibody (N-Terminus) IHC-plus; CERS6; Ceramide synthase 6; Longevity assurance homolog 6; LASS6; Human CerS6; anti-CERS6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
At least two isoforms of LASS6 are known to exist. This antibody is predicted not to cross-react with LASS5.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS containing 0.02% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
392
Applicable Applications for anti-CERS6 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Target Species
Human
Immunogen Description
A 13 amino acid peptide near the amino terminus of human LASS6.
Immunogen Type
Synthetic peptide
Immunogen
CerS6 / LASS6 antibody was raised against a 13 amino acid peptide near the amino terminus of human LASS6.
Antigen Modification
N-Terminus
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-LASS6 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-LASS6 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC)

(Anti-LASS6 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-LASS6 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of LASS6 in Mouse Brain cells with LASS6 antibody at 5 ug/ml.)

Immunofluorescence (IF) (Immunofluorescence of LASS6 in Mouse Brain cells with LASS6 antibody at 5 ug/ml.)

Western Blot (WB)

(Western blot of LASS6 in rat brain tissue lysate with LASS6 antibody at (A) 1 and (B) 2 ug/ml.)

Western Blot (WB) (Western blot of LASS6 in rat brain tissue lysate with LASS6 antibody at (A) 1 and (B) 2 ug/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45,794 Da
NCBI Official Full Name
ceramide synthase 6 isoform 1
NCBI Official Synonym Full Names
ceramide synthase 6
NCBI Official Symbol
CERS6
NCBI Official Synonym Symbols
CERS5; LASS6
NCBI Protein Information
ceramide synthase 6; longevity assurance homolog 6; LAG1 homolog, ceramide synthase 6
UniProt Protein Name
Ceramide synthase 6
Protein Family
UniProt Gene Name
CERS6
UniProt Synonym Gene Names
LASS6; CerS6
UniProt Entry Name
CERS6_HUMAN

Uniprot Description

LASS6: May be involved in sphingolipid synthesis or its regulation.

Protein type: DNA-binding; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2q24.3

Cellular Component: endoplasmic reticulum membrane; nuclear membrane; membrane; endoplasmic reticulum; integral to membrane

Molecular Function: DNA binding; sphingosine N-acyltransferase activity

Biological Process: sphingolipid metabolic process; sphingolipid biosynthetic process; ceramide biosynthetic process

Research Articles on CERS6

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Product Notes

The CERS6 cers6 (Catalog #AAA242665) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human CerS6 / LASS6 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CerS6 / LASS6 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the CERS6 cers6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CerS6 / LASS6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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