Western Blot (WB)
(Sample Data: Western blot analysis of BAG1 in PC-3 cell lysate with BAG1 antibody at (A) 1 and (B) 2 ug/ml.)
Rabbit BAG1 Polyclonal Antibody | anti-BAG1 antibody
Anti-BAG1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity chromatography
Synonyms
BAG1; Polyclonal Antibody; Anti-BAG1; anti-BAG1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit, IgG
Specificity
Recognizes the BAG1 protein
Purity/Purification
Affinity chromatography
Form/Format
PBS + 0.02% sodium azide
Applicable Applications for anti-BAG1 antibody
Western Blot (WB), ELISA
Immunogen
BAG1 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human BAG1
Preparation and Storage
Store at 4 degree C (add 0.1% NaN3) for several months, and at -20 degree C for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
1 year at -20 degree C from date of shipment
1 year at -20 degree C from date of shipment
Western Blot (WB)
(Sample Data: Western blot analysis of BAG1 in PC-3 cell lysate with BAG1 antibody at (A) 1 and (B) 2 ug/ml.)
Western Blot (WB)
(Sample Data: Western blot analysis of BAG1 in PC-3 cell lysate with BAG1 antibody at (A) 1 and (B) 2 ug/ml.)
Related Product Information for anti-BAG1 antibody
BAG1 (also known as BCL2-associated athanogene) is a membrane protein rich in glutamic acid residues that binds to BCL2 and blocks apoptosis or programmed cell death (1). The BAG1-BCL2 complex enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms (2). Overexpression of BAG1 in 3T3 fibroblasts prevents apoptosis in the presence of low serum. BAG1 has also been shown to interact with activated glucocorticoid, androgen, estrogen and progesterone receptors. Binding to these receptors by BAG1 is dependent on receptor activation.
Product Categories/Family for anti-BAG1 antibody
References
1. Tang, S.C. BAG-1, an anti-apoptotic tumour marker.". IUBMB Life, 2003; 53 (2): 99-105.
2. Clemo, N.K. et al: The role of the retinoblastoma protein (Rb) in the nuclear localization of BAG-1: implications for colorectal tumour cell survival.".Biochem. Soc. Trans.2005; 33 (Pt 4): 676-8.
2. Clemo, N.K. et al: The role of the retinoblastoma protein (Rb) in the nuclear localization of BAG-1: implications for colorectal tumour cell survival.".Biochem. Soc. Trans.2005; 33 (Pt 4): 676-8.
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Product Notes
The BAG1 (Catalog #AAA515860) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-BAG1 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BAG1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA. Researchers should empirically determine the suitability of the BAG1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BAG1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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