SDS-Page
(Recombinant NAT10 protein 10% SDS-PAGE gel with Coomassie blue staining MW: 117 kDa Purity: >95%)
NAT10 recombinant protein
Recombinant NAT10 protein
Synonyms
NAT10; Recombinant NAT10 protein; N-Acetyltransferase 10; NAT10 recombinant protein
Host
Baculovirus
Form/Format
Recombinant NAT10 protein is supplied in 25mM HEPES-NaOH pH7.5, 300mM NaCl, 10% glycerol, 0.04% Triton X-100, and 0.5mM TCEP.
Protein Species
Human
Protein Details
Recombinant NAT10 protein was expressed in baculovirus expression system as the full length protein (accession number NP_078938.3) with a N-terminal DYKDDDDK tag.
Notes
This product was manufactured as described in Protein Details. Where possible, We has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for a given product is shown on the lot-specific Technical Data Sheet.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
Shipping Temp: Dry Ice
SDS-Page
(Recombinant NAT10 protein 10% SDS-PAGE gel with Coomassie blue staining MW: 117 kDa Purity: >95%)
SDS-Page
(Recombinant NAT10 protein 10% SDS-PAGE gel with Coomassie blue staining MW: 117 kDa Purity: >95%)
Related Product Information for NAT10 recombinant protein
Background: NAT10 (N-Acetyltransferase 10) is a RNA cytidine acetyltransferase that catalyzes the formation of N(4)- acetylcytidine (ac4C) modification on mRNAs, 18S rRNA and tRNAs and mediates the formation of ac4C at position 1842 in 18S rRNA. NAT10 requires the tRNA-binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. In addition to RNA acetyltransferase activity, NAT10 is also able to acetylate lysine residues of proteins, such as histones, microtubules, p53/TP53 and MDM2, in vitro. It activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. NAT10 involved in the regulation of centrosome duplication by acetylating CENATAC during mitosis, promoting SASS6 proteasome degradation.
Product Categories/Family for NAT10 recombinant protein
NCBI and Uniprot Product Information
Molecular Weight
Molecular weight of the protein is 117kDa
Protein Family
Similar Products
Product Notes
The NAT10 (Catalog #AAA389420) is a Recombinant Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NAT10, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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