SDS-Page
(Recombinant TRMT6 protein gel 8% SDS-PAGE Coomassie staining MW: 57 kDa Purity: >85%)
TRMT6 recombinant protein
Recombinant TRMT6 protein
Synonyms
TRMT6; Recombinant TRMT6 protein; TRNA Methyltransferase 6; MRNA Methyladenosine-N(1)-Methyltransferase Non-Catalytic Subunit TRM6; TRMT6 recombinant protein
Host
Baculovirus
Form/Format
Recombinant TRMT6 protein is supplied in 25mM HEPES-NaOH pH7.5, 300mM NaCl, 10% glycerol, 0.04% Triton X-100, and 0.5mM TCEP.
Protein Species
Human
Tag
DYKDDDDK-Tag
Notes
This product was manufactured as described in Protein Details. Where possible, We has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for a given product is shown on the lot-specific Technical Data Sheet.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
Shipping Temp: Dry Ice
SDS-Page
(Recombinant TRMT6 protein gel 8% SDS-PAGE Coomassie staining MW: 57 kDa Purity: >85%)
SDS-Page
(Recombinant TRMT6 protein gel 8% SDS-PAGE Coomassie staining MW: 57 kDa Purity: >85%)
Related Product Information for TRMT6 recombinant protein
Short Description: Recombinant TRMT6 protein was expressed in a baculovirus expression system as the full-length protein (accession number NP_057023.2) with an N-terminal DYKDDDDK-Tag. The molecular weight of the protein is 57 kDa.
Background: TRMT6 (TRNA Methyltransferase 6), is a member of the tRNA methyltransferase protein 6 family. It's the substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Together with the TRMT61A catalytic subunit, part of a mRNA N(1)-methyltransferase complex that mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs. N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries. Modified 1-methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. A similar protein in yeast is part of a two component methyltransferase, which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs.
Background: TRMT6 (TRNA Methyltransferase 6), is a member of the tRNA methyltransferase protein 6 family. It's the substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Together with the TRMT61A catalytic subunit, part of a mRNA N(1)-methyltransferase complex that mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs. N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries. Modified 1-methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. A similar protein in yeast is part of a two component methyltransferase, which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs.
Product Categories/Family for TRMT6 recombinant protein
NCBI and Uniprot Product Information
Molecular Weight
Molecular weight of the protein is 57kDa
Similar Products
Product Notes
The TRMT6 (Catalog #AAA389240) is a Recombinant Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "TRMT6, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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