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Western Blot (WB) (Figure 1: Western blot analysis using TDGF1 mAb against HEK293 (1) and TDGF1-hIgGFc transfected HEK293 (2) cell lysate.)

Mouse anti-Human TDGF1 Antibody | anti-TDGF1 antibody

TDGF1 Antibody

Gene Names
TDGF1; CR; CRGF; CRIPTO
Reactivity
Human
Applications
Western Blot, ELISA
Synonyms
TDGF1; TDGF1 Antibody; CR; CRGF; CRIPTO; anti-TDGF1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Isotype
IgG1
Clone Number
3A6
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
172
Applicable Applications for anti-TDGF1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
ELISA: 1:10000
Immunogen
Purified recombinant fragment of human TDGF1 expressed in E. Coli.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C.

Western Blot (WB)

(Figure 1: Western blot analysis using TDGF1 mAb against HEK293 (1) and TDGF1-hIgGFc transfected HEK293 (2) cell lysate.)

Western Blot (WB) (Figure 1: Western blot analysis using TDGF1 mAb against HEK293 (1) and TDGF1-hIgGFc transfected HEK293 (2) cell lysate.)

Testing Data

Testing Data
Related Product Information for anti-TDGF1 antibody
This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects.The cripto gene is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. It could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.Tissue specificity: Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
21kDa
NCBI Official Full Name
teratocarcinoma-derived growth factor 1 isoform 2
NCBI Official Synonym Full Names
teratocarcinoma-derived growth factor 1
NCBI Official Symbol
TDGF1
NCBI Official Synonym Symbols
CR; CRGF; CRIPTO
NCBI Protein Information
teratocarcinoma-derived growth factor 1
UniProt Protein Name
Teratocarcinoma-derived growth factor 1
UniProt Gene Name
TDGF1
UniProt Synonym Gene Names
CRIPTO; CRGF

NCBI Description

This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

Uniprot Description

GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells (PubMed:27881714). Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm (PubMed:11909953).

Research Articles on TDGF1

Similar Products

Product Notes

The TDGF1 tdgf1 (Catalog #AAA850065) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TDGF1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TDGF1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000 ELISA: 1:10000. Researchers should empirically determine the suitability of the TDGF1 tdgf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TDGF1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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