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Flow Cytometry (FC/FACS) (Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD352 (hsF6.4.20) PE antibody (10ul reagent/100ul of peripheral whole blood).)

Mouse anti-Human CD352 Antibody | anti-CD352 antibody

Anti-Hu CD352 PE

Gene Names
SLAMF6; KALI; NTBA; CD352; KALIb; Ly108; NTB-A; SF2000
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Synonyms
CD352; Anti-Hu CD352 PE; SLAMF6; KALI; NTBA; Ly108; SF2000; SLAM family member 6; anti-CD352 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Isotype
Mouse IgG1
Clone Number
hsF6.4.20
Specificity
The mouse monoclonal antibody hsF6.4.20 recognizes an extracellular epitope of CD352, a transmembrane glycoprotein expressed on NK, T and B cells.
Purity/Purification
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Form/Format
Stabilizing phosphate buffered saline (PBS), pH7.4, 15mM sodium azide
Applicable Applications for anti-CD352 antibody
Flow Cytometry (FC/FACS)(QC tested)
Application Notes
FC/FACS: The reagent is designed for analysis of human blood cells using 10ul reagent/100ul of whole blood or 106 cells in a suspension. The content of a vial (1ml) is sufficient for 100 tests.
Conjugation
PE
Immunogen
CD352 transfectants
Excitation Laser
blue (488 nm)
Preparation and Storage
Store at 2-8 degree C. Protect from prolonged exposure to light. Do not freeze.

Flow Cytometry (FC/FACS)

(Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD352 (hsF6.4.20) PE antibody (10ul reagent/100ul of peripheral whole blood).)

Flow Cytometry (FC/FACS) (Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD352 (hsF6.4.20) PE antibody (10ul reagent/100ul of peripheral whole blood).)

Flow Cytometry (FC/FACS)

(Separation of human CD352 positive lymphocytes(red-filled) from monocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD352 (hsF6.4.20) PE antibody (10ul reagent/100ul of peripheral whole blood).)

Flow Cytometry (FC/FACS) (Separation of human CD352 positive lymphocytes(red-filled) from monocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD352 (hsF6.4.20) PE antibody (10ul reagent/100ul of peripheral whole blood).)
Related Product Information for anti-CD352 antibody
CD352, also known as SLAMF6 (SLAM family member 6) is a type I transmembrane glycoprotein expressed on NK cells, T cells, and B cells, and serves as a coreceptor for them. Besides association of its tyrosine phosphorylated intracellular domain with SH2D1A protein, it associates also with SH2 domain-containing phosphatases, which can modulate the signaling. Multiple CD352 isoforms have been identified.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,976 Da
NCBI Official Full Name
SLAM family member 6 isoform 1
NCBI Official Synonym Full Names
SLAM family member 6
NCBI Official Symbol
SLAMF6
NCBI Official Synonym Symbols
KALI; NTBA; CD352; KALIb; Ly108; NTB-A; SF2000
NCBI Protein Information
SLAM family member 6; NK-T-B-antigen; NTBA receptor; activating NK receptor; natural killer-, T- and B-cell antigen
UniProt Protein Name
SLAM family member 6
UniProt Gene Name
SLAMF6
UniProt Synonym Gene Names
KALI; NTB-A
UniProt Entry Name
SLAF6_HUMAN

NCBI Description

The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010]

Uniprot Description

SLAMF6: Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: integral to membrane; plasma membrane

Molecular Function: receptor activity

Research Articles on CD352

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Product Notes

The CD352 slamf6 (Catalog #AAA1802266) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Hu CD352 PE reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD352 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS)(QC tested). FC/FACS: The reagent is designed for analysis of human blood cells using 10ul reagent/100ul of whole blood or 106 cells in a suspension. The content of a vial (1ml) is sufficient for 100 tests. Researchers should empirically determine the suitability of the CD352 slamf6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD352, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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