Western Blot (WB)
(Western Blot analysis of DcR2 in HeLa whole cell lysate with anti-DcR2 (ID) at 1:1000 dilution.)
Rabbit DcR2 Polyclonal Antibody | anti-Dcr-2 antibody
DcR2, ID (TRAIL-R4, TRUNDD, Decoy Receptor2, TNF receptor related receptor for TRAIL, TNFRSF10D, TRAIL receptor 4, TRAIL receptor with a truncated death domain, TRUNDD, Tumor necrosis factor receptor superfamily member 10D precursor)
Gene Names
Dcr-2; cg6493; CG6493; dcr-2; DCR-2; dcr2; Dcr2; DCR2; dicer; Dicer; DICER; dicer2; DmelCG6493
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by affinity chromatography.
Synonyms
DcR2; Polyclonal Antibody; ID (TRAIL-R4; TRUNDD; Decoy Receptor2; TNF receptor related receptor for TRAIL; TNFRSF10D; TRAIL receptor 4; TRAIL receptor with a truncated death domain; Tumor necrosis factor receptor superfamily member 10D precursor); Anti -DcR2; anti-Dcr-2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human DcR2. An approximate 34kD band can be detected. Species crossreactivity: Mouse and rat..
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Purified by affinity chromatography.
Form/Format
Supplied as a liquid in PBS with 0.02% sodium azide.
Applicable Applications for anti-Dcr-2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:1,000-1:2,000
Dilution: Western Blot: 1:1,000-1:2,000
Immunogen
Peptide corresponding to amino acids 249 to 263 of human DcR2 precursor.
Positive Control
HeLa cell lysate
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C or colder. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Western Blot (WB)
(Western Blot analysis of DcR2 in HeLa whole cell lysate with anti-DcR2 (ID) at 1:1000 dilution.)
Western Blot (WB)
(Western Blot analysis of DcR2 in HeLa whole cell lysate with anti-DcR2 (ID) at 1:1000 dilution.)
Immunohistochemistry (IHC)
(Immunohistochemical staining of HeLa cells using anti-DcR2 (ID) at 10ug/ml.)
Immunohistochemistry (IHC)
(Immunohistochemical staining of HeLa cells using anti-DcR2 (ID) at 10ug/ml.)
Related Product Information for anti-Dcr-2 antibody
Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor. Another member of the TRAIL receptor family was more recently identified and designated DcR2, TRAIL-R4, or TRUNDD. DcR2 has an extracellular TRAIL-binding domain but lacks intracellular death domain and does not induce apoptosis. Like DR4 and DR5, DcR2 transcript is widely expressed in normal human tissues. Overexpression of DcR2 attenuated TRAIL-induced apoptosis.
Product Categories/Family for anti-Dcr-2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
Dicer-2
NCBI Official Synonym Full Names
Dicer-2
NCBI Official Symbol
Dcr-2
NCBI Official Synonym Symbols
cg6493; CG6493; dcr-2; DCR-2; dcr2; Dcr2; DCR2; dicer; Dicer; DICER; dicer2; DmelCG6493
NCBI Protein Information
CG6493 gene product from transcript CG6493-RA; Dicer-2; CG6493-PA; Dcr-2-PA; Dicer2; dicer 2
Research Articles on Dcr-2
Similar Products
Product Notes
The Dcr-2 (Catalog #AAA626870) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DcR2, ID (TRAIL-R4, TRUNDD, Decoy Receptor2, TNF receptor related receptor for TRAIL, TNFRSF10D, TRAIL receptor 4, TRAIL receptor with a truncated death domain, TRUNDD, Tumor necrosis factor receptor superfamily member 10D precursor) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DcR2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 1:1,000-1:2,000. Researchers should empirically determine the suitability of the Dcr-2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DcR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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