CD352 recombinant protein

Recombinant Human CD352 protein, C-His Tag

Cat. Num. AAA1560649

• Gene Names: SLAMF6; KALI; NTBA; CD352; KALIb; Ly108; NTB-A; SF2000
• Purity: >90% as determined by SDS-PAGE
• Synonyms: CD352; Recombinant Human CD352 protein; C-His Tag; KALI; KALIb; Ly108; NTB-A; NTBA; SF2000; CD352 recombinant protein

• Host: Mammalian cells
• Purity/Purification: >90% as determined by SDS-PAGE
• Form/Format: Lyophilized. Lyophilized from PBS pH 7.4, 5% Trehalose, 5% Mannose, 1mM EDTA.

• Tag: C-His Tag
• Species: Homo sapiens (Human)
• Endotoxin Level: <1.0EU per ug of the protein as determined by the LAL method.
• Protein Construction: A DNA sequence encoding the human SLAMF6 (Met1-Met226) was fused with the C-terminal His Tag
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Preparation and Storage: Store at 2 to 8 degree C for one week. Store at -20 to -80 degree C for twelve months from the date of receipt. Use a manual defrost freezer and avoid repeated freeze thaw cycles.; In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

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Product Categories/Family for CD352 recombinant protein

Protein

NCBI and Uniprot Product Information

• NCBI GI #: 296040491
• NCBI GeneID: 114836
• NCBI Accession #: NP_001171643.1
• NCBI GenBank Nucleotide #: NM_001184714.1
• UniProt Accession #: Q96DU3; Q14CF0; Q5TAS4; Q5TAS6; Q5TAT3; Q96DV0; A6NMW2; B2R8X8
• Molecular Weight: 24,976 Da
• NCBI Official Full Name: SLAM family member 6 isoform 1
• NCBI Official Synonym Full Names: SLAM family member 6
• NCBI Official Symbol: SLAMF6
• NCBI Official Synonym Symbols: KALI; NTBA; CD352; KALIb; Ly108; NTB-A; SF2000
• NCBI Protein Information: SLAM family member 6; NK-T-B-antigen; NTBA receptor; activating NK receptor; natural killer-, T- and B-cell antigen
• UniProt Protein Name: SLAM family member 6
• UniProt Gene Name: SLAMF6
• UniProt Synonym Gene Names: KALI; NTB-A
• UniProt Entry Name: SLAF6_HUMAN

NCBI Description

The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010]

Uniprot Description

SLAMF6: Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: integral to membrane; plasma membrane

Molecular Function: receptor activity