Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Vascular Endothelial cell Growth Factor B (VEGF-B) Standard Curve.)
Mouse Vascular Endothelial Cell Growth Factor B (VEGF-B) ELISA Kit | VEGF-B elisa kit
Mouse Vascular Endothelial Cell Growth Factor B (VEGF-B) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Vascular Endothelial cell Growth Factor B (VEGF-B) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Vascular Endothelial cell Growth Factor B (VEGF-B) Standard Curve.)
Background: Vascular endothelial growth factor B is a growth factor that belongs to the vascular endothelial growth factor family of which VEGF-A is the best known member. In contrast to VEGF-A, VEGF-B plays a less pronounced role in the vascular system: whereas VEGF-A is important for the formation of blood vessels, such as during development or in pathological conditions, VEGF-B seems only to play in role in the maintenance of newly formed blood vessels during pathological conditions. VEGF-B plays also an important role on several types of neurons. It is important for the protection of neurons in the retina and the cerebral cortex during stroke and of motoneurons during motor neuron diseases such as amyotrophic lateral sclerosis.VEGF-B exerts its effects via the FLT1 receptor.
NCBI and Uniprot Product Information
Uniprot Description
VEGFB: Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. Homodimer; disulfide-linked. Can also form heterodimer with VEGF. Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas. Belongs to the PDGF/VEGF growth factor family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide; Cell cycle regulation; Cytokine
Cellular Component: extracellular region; extracellular space; intracellular; membrane
Molecular Function: chemoattractant activity; growth factor activity; heparin binding; protein heterodimerization activity; protein homodimerization activity; vascular endothelial growth factor receptor 1 binding
Biological Process: angiogenesis; cardiac muscle contraction; cell differentiation; heart development; induction of positive chemotaxis; multicellular organismal development; negative regulation of apoptosis; negative regulation of neuron apoptosis; positive chemotaxis; positive regulation of cell division; positive regulation of endothelial cell proliferation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of protein kinase B signaling cascade; positive regulation of vascular endothelial growth factor receptor signaling pathway; protein amino acid O-linked glycosylation
Research Articles on VEGF-B
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Product Notes
The Mouse VEGF-B vegfb (Catalog #AAA9718173) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9718173 ELISA Kit recognizes Mouse VEGF-B. It is sometimes possible for the material contained within the vial of "Vascular Endothelial Cell Growth Factor B (VEGF-B), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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