Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Rat Vascular Endothelial cell Growth Factor C (VEGF-C) Standard Curve.)
Rat Vascular Endothelial Cell Growth Factor C (VEGF-C) ELISA Kit | VEGF-C elisa kit
Rat Vascular Endothelial Cell Growth Factor C (VEGF-C) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Rat Vascular Endothelial cell Growth Factor C (VEGF-C) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Rat Vascular Endothelial cell Growth Factor C (VEGF-C) Standard Curve.)
Background: Vascular endothelial growth factor receptor-1 was originally discovered through the screening of a human placental cDNA library. It is a receptor tyrosine kinase (RTK) specific for the angiogenic factors VEGF (VEGF-A), PlGF, and VEGF-B. VEGF R1 is expressed in two forms via alternate splicing at the pre-mRNA level: a full-length, membrane bound receptor capable of transducing signal, and a truncated, soluble receptor (sVEGF R1) capable of sequestering ligand or dimerizing with full-length receptor and preventing signal transduction. Although VEGF R1 null mutations are lethal, deletions of the kinase domain are not, suggesting that the soluble form, or at least the extracellular domain, is all that is necessary for normal vascular development.
NCBI and Uniprot Product Information
NCBI Description
platelet-derived growth factor/vascular derived growth factor (PDGF/VEGF); active in angiogenesis and endothelial cell growth [RGD, Feb 2006]
Uniprot Description
VEGFC: Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. Homodimer; non-covalent and antiparallel. Spleen, lymph node, thymus, appendix, bone marrow, heart, placenta, ovary, skeletal muscle, prostate, testis, colon and small intestine and fetal liver, lung and kidney, but not in peripheral blood lymphocyte. Belongs to the PDGF/VEGF growth factor family.
Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis; Cytokine; Cell cycle regulation
Cellular Component: extracellular space; membrane
Molecular Function: growth factor activity; vascular endothelial growth factor receptor 3 binding; chemoattractant activity
Biological Process: response to drug; positive regulation of neuroblast proliferation; positive regulation of blood vessel endothelial cell migration; positive regulation of protein amino acid autophosphorylation; regulation of angiogenesis; induction of positive chemotaxis; negative regulation of cell proliferation; organ morphogenesis; positive regulation of angiogenesis; positive regulation of peptidyl-tyrosine phosphorylation; morphogenesis of embryonic epithelium; positive chemotaxis; positive regulation of protein secretion; positive regulation of cell division; regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of cell proliferation; angiogenesis; negative regulation of blood pressure; positive regulation of cell-matrix adhesion; vascular endothelial growth factor receptor signaling pathway; positive regulation of epithelial cell proliferation
Research Articles on VEGF-C
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Product Notes
The Rat VEGF-C vegfc (Catalog #AAA9711609) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9711609 ELISA Kit recognizes Rat VEGF-C. It is sometimes possible for the material contained within the vial of "Vascular Endothelial Cell Growth Factor C (VEGF-C), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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