Mouse Tissue Factor (TF) ELISA Kit | TF elisa kit

Mouse Tissue Factor (TF) ELISA Kit

Cat. Num. AAA454597

• Gene Names: F3; TF; Cf3; Cf-3; CD142; AA409063
• Reactivity: Mouse
• Synonyms: Tissue Factor (TF); Mouse Tissue Factor (TF) ELISA Kit; CD142; FIII; F3; TFA; Thromboplastin; Coagulation Factor III; TF elisa kit

• Reactivity: Mouse
• Sequence Length: 294

• Samples: Plasma.
• Assay Type: Sandwich
• Detection Range: 6.25-400pg/mL
• Sensitivity: 2.31pg/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 170172540
• NCBI GeneID: 14066
• NCBI Accession #: NP_034301.3
• NCBI GenBank Nucleotide #: NM_010171.3
• UniProt Accession #: P20352
• Molecular Weight: 32,935 Da
• NCBI Official Full Name: tissue factor
• NCBI Official Synonym Full Names: coagulation factor III
• NCBI Official Symbol: F3
• NCBI Official Synonym Symbols: TF; Cf3; Cf-3; CD142; AA409063
• NCBI Protein Information: tissue factor
• UniProt Protein Name: Tissue factor
• Protein Family: Tissue factor
• UniProt Gene Name: F3
• UniProt Synonym Gene Names: Cf-3; Cf3; TF

NCBI Description

This gene encodes a membrane-bound glycoprotein that forms the primary physiological initiator of the blood coagulation process following vascular damage. The encoded protein binds to coagulation factor VIIa and the ensuing complex catalyzes the proteolytic activation of coagulation factors IX and X. Mice lacking encoded protein die in utero resulting from massive hemorrhaging in both extraembryonic and embryonic vessels. A severe deficiency of the encoded protein in mice results in impaired uterine homeostasis, shorter life spans due to spontaneous fatal hemorrhages and cardiac fibrosis. [provided by RefSeq, Aug 2015]

Uniprot Description

Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.