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Western Blot (WB) (Western blot analysis of IRAK in HeLa lysates with IRAK antibody at (A) 1 and (B) 2 ug/mL.)

Mouse anti-Human, Mouse IRAK Monoclonal Antibody | anti-IRAK antibody

IRAK Monoclonal Antibody

Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Immunoaffinity chromotography purified IgG
Synonyms
IRAK; Monoclonal Antibody; IRAK Monoclonal Antibody; IRAK (1F12C1); IL-1-Receptor Associated Kinase; anti-IRAK antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Clone Number
1F12C1
Purity/Purification
Immunoaffinity chromotography purified IgG
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Applicable Applications for anti-IRAK antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen Type
Recombinant protein
Immunogen Description
Recombinant protein corresponding to amino acids 618 - 712 of human IRAK.
Target Name
IRAK
Preparation and Storage
Can be stored at -20 degree C, stable for one year.

Western Blot (WB)

(Western blot analysis of IRAK in HeLa lysates with IRAK antibody at (A) 1 and (B) 2 ug/mL.)

Western Blot (WB) (Western blot analysis of IRAK in HeLa lysates with IRAK antibody at (A) 1 and (B) 2 ug/mL.)

Immunohistochemistry (IHC)

(Immunohistochemistry of IRAK in rat liver tissue with IRAK antibody at 2.5 ug/mL.)

Immunohistochemistry (IHC) (Immunohistochemistry of IRAK in rat liver tissue with IRAK antibody at 2.5 ug/mL.)
Related Product Information for anti-IRAK antibody
Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently. IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. IRAK mediates a signaling cascade leading to NF-kB activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF).
Product Categories/Family for anti-IRAK antibody

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Product Notes

The IRAK (Catalog #AAA9400127) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The IRAK Monoclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IRAK can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the IRAK for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IRAK, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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