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Potassium voltage-gated channel subfamily E member 1-like protein (KCNE1L) Recombinant Protein | KCNE1L recombinant protein

Recombinant Human Potassium voltage-gated channel subfamily E member 1-like protein (KCNE1L), partial

Gene Names
KCNE5; KCNE1L
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Potassium voltage-gated channel subfamily E member 1-like protein (KCNE1L); Recombinant Human Potassium voltage-gated channel subfamily E member 1-like protein (KCNE1L); partial; KCNE1L recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
82-142
Sequence
TRSRKLVEA KDEPSQACAE HEWAPGGALT ADAEAAAGSQ AEGRRQLASE GLPALAQGAE RV
Sequence Length
61
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for KCNE1L recombinant protein
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a membrane protein which has sequence similarity to the KCNE1 gene product, a member of the potassium channel, voltage-gated, isk-related subfamily. This intronless gene is deleted in AMME contiguous gene syndrome and may be involved in the cardiac and neurologic abnormalities found in the AMME contiguous gene syndrome.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14,993 Da
NCBI Official Full Name
potassium voltage-gated channel subfamily E regulatory beta subunit 5
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily E regulatory subunit 5
NCBI Official Symbol
KCNE5
NCBI Official Synonym Symbols
KCNE1L
NCBI Protein Information
potassium voltage-gated channel subfamily E regulatory beta subunit 5
UniProt Protein Name
Potassium voltage-gated channel subfamily E regulatory beta subunit 5
UniProt Gene Name
KCNE5

NCBI Description

This gene encodes a member of a family of single pass transmembrane domain proteins that function as ancillary subunits to voltage-gated potassium channels. Members of this family affect diverse processes in potassium channel regulation, including ion selectivity, voltage dependence, and anterograde recycling from the plasma membrane. Variants of this gene are associated with idiopathic ventricular fibrillation and Brugada syndrome. [provided by RefSeq, Nov 2016]

Uniprot Description

Potassium channel ancillary subunit that is essential for generation of some native K+ currents by virtue of formation of heteromeric ion channel complex with voltage-gated potassium (Kv) channel pore-forming alpha subunits. Functions as an inhibitory beta-subunit of the repolarizing cardiac potassium ion channel KCNQ1.

Research Articles on KCNE1L

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Product Notes

The KCNE1L kcne5 (Catalog #AAA1313757) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 82-142. The amino acid sequence is listed below: TRSRKLVEA KDEPSQACAE HEWAPGGALT ADAEAAAGSQ AEGRRQLASE GLPALAQGAE RV. It is sometimes possible for the material contained within the vial of "Potassium voltage-gated channel subfamily E member 1-like protein (KCNE1L), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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