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Immunohistochemistry - Paraffin (IHC) (Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit anti-Human KCNE5 Polyclonal Antibody | anti-KCNE5 antibody

Anti-KCNE5 Antibody (aa67-96) IHC-plus

Gene Names
KCNE5; KCNE1L
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunoaffinity purified
Synonyms
KCNE5; Polyclonal Antibody; Anti-KCNE5 Antibody (aa67-96) IHC-plus; Rabbit Polyclonal to Human KCNE5; Human KCNE5; AMMECR2; KCNE1-like; KCNE1L; AMMECR2 protein; anti-KCNE5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Human KCNE1-like / KCNE1L
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.09% sodium azide
Sequence Length
142
Applicable Applications for anti-KCNE5 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P (1:100)
WB (1:1000)
Immunogen
KCNE5 antibody was raised against kLH-conjugated synthetic peptide from internal region of human KCE1L.
Immunogen Description
KLH-conjugated synthetic peptide from internal region of human KCE1L.
Immunogen Type
Synthetic peptide
Antigen Modification
aa67-96
Target Species
Human
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months.
For long term storage store at -20 degree C.

Immunohistochemistry - Paraffin (IHC)

(Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry - Paraffin (IHC) (Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot of KCE1L Antibody in NCI-H460 cell line lysates (35 ug/lane). KCE1L (arrow) was detected using the purified antibody.)

Western Blot (WB) (Western blot of KCE1L Antibody in NCI-H460 cell line lysates (35 ug/lane). KCE1L (arrow) was detected using the purified antibody.)
Related Product Information for anti-KCNE5 antibody
KCNE5 Antibody, AMMECR2 Antibody, KCNE1-like Antibody, KCNE1L Antibody, AMMECR2 protein Antibody Description: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14,993 Da
NCBI Official Full Name
potassium voltage-gated channel subfamily E regulatory beta subunit 5
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily E regulatory subunit 5
NCBI Official Symbol
KCNE5
NCBI Official Synonym Symbols
KCNE1L
NCBI Protein Information
potassium voltage-gated channel subfamily E regulatory beta subunit 5
UniProt Protein Name
Potassium voltage-gated channel subfamily E regulatory beta subunit 5
UniProt Gene Name
KCNE5
UniProt Entry Name
KCNE5_HUMAN

NCBI Description

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a membrane protein which has sequence similarity to the KCNE1 gene product, a member of the potassium channel, voltage-gated, isk-related subfamily. This intronless gene is deleted in AMME contiguous gene syndrome and may be involved in the cardiac and neurologic abnormalities found in the AMME contiguous gene syndrome. [provided by RefSeq, Jul 2008]

Uniprot Description

KCNE1L: Defects in KCNE1L are involved in Alport syndrome with mental retardation midface hypoplasia and elliptocytosis (ATS-MR). A X-linked contiguous gene deletion syndrome characterized by glomerulonephritis, deafness, mental retardation, midface hypoplasia and elliptocytosis. Belongs to the potassium channel KCNE family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq22.3

Cellular Component: plasma membrane; voltage-gated potassium channel complex

Molecular Function: potassium channel regulator activity; protein binding; voltage-gated potassium channel activity

Biological Process: cardiac muscle contraction; regulation of heart contraction

Research Articles on KCNE5

Similar Products

Product Notes

The KCNE5 kcne5 (Catalog #AAA2400287) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-KCNE5 Antibody (aa67-96) IHC-plus reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KCNE5 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P (1:100) WB (1:1000). Researchers should empirically determine the suitability of the KCNE5 kcne5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNE5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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